gene

adnp

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adnp: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

106Connections
0Hypotheses
0Analyses
17Outgoing
4Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolADNP
Protein TypeTranscription Factor
FunctionADNP encodes a 1,102 amino acid protein containing a homeobox domain, nine zinc fingers, and a PxVxL motif that mediates interaction with the SWI/SNF chromatin remodeling complex through HP1.
Molecular Weight124 kDa
Amino Acids102 aa
PathwaysAutophagy, Epigenetic, Wnt
Ensembl IDENSG00000101126
GeneCardsADNP
Human Protein AtlasADNP
Associated DiseasesMs, Aging
InteractionsALZHEIMER, P2X7 RECEPTOR, P2X7
KG Connections21 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (15)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

Davunetide (AL-108) PSP Trial

clinical · 2927 words

Gender Differences in Progressive Supranuclear Palsy

disease · 2584 words

Neuroprotective Peptides for Neurodegenerative Diseases

therapeutic · 2096 words

Pathway Diagram

flowchart TD
    N0["adnp"]
    N1["SYNAPSE"]
    N0 -->|"regulates"| N1
    N2["Neuroprotection"]
    N0 -->|"regulates"| N2
    N0 -->|"expressed in"| N1
    N3["GENE EXPRESSION"]
    N0 -->|"expressed in"| N3
    N4["ALZHEIMER"]
    N0 -->|"activates"| N4
    N5["Alzheimer'S Disease"]
    N0 -->|"activates"| N5
    N6["disease"]
    N0 -->|"activates"| N6
    N7["ALZHEIMER'S"]
    N0 -->|"activates"| N7
    N8["Astrocytes"]
    N0 -->|"inhibits"| N8
    N9["Astrocyte"]
    N0 -->|"inhibits"| N9
    N10["APP/PS1"]
    N0 -->|"inhibits"| N10
    N0 -->|"expressed in"| N8
    N0 -->|"expressed in"| N9
    N11["P2X7 RECEPTOR"]
    N0 -->|"inhibits"| N11

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    class N4 gene
    class N5 disease
    class N6 disease
    class N11 protein

Outgoing (83)

TargetRelationTypeStr
SYNAPSEregulatesconcept0.50
Neuroprotectionregulatesprocess0.50
SYNAPSEexpressed_inconcept0.50
GENE EXPRESSIONexpressed_inconcept0.50
ALZHEIMERactivatesgene0.50

Incoming (23)

SourceRelationTypeStr
AUTISMregulatesdisease0.50
AUTISMprotects_againstdisease0.50
SCHIZOPHRENIAactivatesdisease0.50
AUTISMinhibitsdisease0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found