YY1

Understanding Entity Pages

This page aggregates everything SciDEX knows about YY1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

YY1 is a gene implicated in neurodegeneration research. Key relationships include: activates, expressed in, therapeutic target. Associated with Aging, Als, Alzheimer. Connected to 74 entities in the SciDEX knowledge graph.

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graph TD
    YY1["<b>YY1</b>"]
    Cardiac{"Cardiac"}
    YY1 -->|"expressed in"| Cardiac
    Ms{"Ms"}
    YY1 -->|"expressed in"| Ms
    Autism{"Autism"}
    YY1 -->|"expressed in"| Autism
    Cancer{"Cancer"}
    YY1 -->|"activates"| Cancer
    YY1 -->|"therapeutic target"| Ms
    YY1 -->|"therapeutic target"| Cancer
    Tumor{"Tumor"}
    YY1 -->|"therapeutic target"| Tumor
    Alzheimer{"Alzheimer"}
    YY1 -->|"regulates"| Alzheimer
    YY1 -->|"interacts with"| Ms
    YY1 -->|"regulates"| Ms
    Diabetes{"Diabetes"}
    YY1 -->|"regulates"| Diabetes
    YY1 -->|"regulates"| Cardiac
    CANCER["CANCER"]
    CANCER -->|"activates"| YY1
    LC3B["LC3B"]
    LC3B -->|"activates"| YY1
    PHAGOCYTOSIS["PHAGOCYTOSIS"]
    PHAGOCYTOSIS -->|"therapeutic target"| YY1
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"therapeutic target"| YY1
    TREM2["TREM2"]
    TREM2 -->|"expressed in"| YY1
    FERROPTOSIS["FERROPTOSIS"]
    FERROPTOSIS -->|"inhibits"| YY1
    GPX4["GPX4"]
    GPX4 -->|"inhibits"| YY1
    DIABETES_MELLITUS["DIABETES MELLITUS"]
    DIABETES_MELLITUS -->|"regulates"| YY1
    RAB7A["RAB7A"]
    RAB7A -->|"regulates"| YY1
    MICROGLIA -->|"inhibits"| YY1
    style YY1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0