Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about TAU PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | TAU PROTEIN |
| Key Genes/Proteins | VPS35, NFKB |
| Related Diseases | Alzheimer's Disease, Tauopathies |
| Linked Hypotheses | 3 hypotheses |
Knowledge base pages for this entity
graph TD
TAU_PROTEIN["TAU PROTEIN"]
style TAU_PROTEIN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
TAU_PROTEIN -.->|"biomarker for"| Alzheimer_s_Disease["Alzheimer's Disease"]
TAU_PROTEIN -.->|"biomarker for"| Tauopathies["Tauopathies"]
TAU_PROTEIN -->|"involved_in"| Hyperphosphorylation["Hyperphosphorylation"]
TAU_PROTEIN -->|"expressed in"| Retina["/Retina/"]
TAU_PROTEIN -->|"causes"| Alzheimer_S_Disease["Alzheimer'S Disease"]
TAU_PROTEIN -->|"interacts"| NFKB([NFKB])
TAU_PROTEIN -->|"causes"| neuronal_damage["neuronal damage"]
TAU_PROTEIN -->|"activates"| Reactive_oxygen_species["Reactive oxygen species"]
Alzheimer_s_Disease -.->|"biomarker for"| TAU_PROTEIN
Cerebrospinal_Fluid["Cerebrospinal Fluid"] -->|"component_of"| TAU_PROTEIN
Post_translational_Modificatio["Post-translational Modifications"] -->|"regulates"| TAU_PROTEIN
MAPT([MAPT]) -->|"encodes"| TAU_PROTEIN
NBR1([NBR1]) -->|"interacts"| TAU_PROTEIN
CBD{"CBD"} -->|"regulates"| TAU_PROTEIN
Cannabidiol{"Cannabidiol"} -.->|"inhibits"| TAU_PROTEIN
FBXW7([FBXW7]) -->|"regulates"| TAU_PROTEIN| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer's Disease | associated_with | disease | 0.95 |
| Alzheimer's Disease | biomarker_for | disease | 0.95 |
| Tauopathies | biomarker_for | disease | 0.95 |
| Tauopathies | involved_in | disease | 0.95 |
| Axonal Structure | regulates | structure | 0.92 |
| Axonal Transport | regulates | process | 0.92 |
| Retina | expressed_in | cell_type | 0.90 |
| NFKB | interacts_with | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| VPS35 | regulates | protein | 0.85 |
| Post-translational Modifications | regulates | process | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||