Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CD206: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| macrophage polarization | biomarker_for | process | 0.85 |
| neuroinflammation | activates | disease | 0.80 |
| Macrophage Subsets | associated_with | cell_type | 0.75 |
| Sarcopenia | biomarker_for | disease | 0.75 |
| M2 anti-inflammatory phenotype | biomarker_for | cell_type | 0.70 |
| Macrophage Subsets | regulates | cell_type | 0.60 |
| NOS2 | activates | gene | 0.60 |
| TNF | activates | gene | 0.60 |
| CD36 | activates | gene | 0.60 |
| CD68 | activates | gene | 0.60 |
| JAK2 | regulates | gene | 0.60 |
| STAT3 | regulates | gene | 0.60 |
| CD86 | activates | gene | 0.60 |
| NLRP3 | activates | gene | 0.60 |
| TLR4 | activates | gene | 0.60 |
| CD80 | activates | gene | 0.60 |
| CD68 | associated_with | gene | 0.60 |
| cancer | associated_with | disease | 0.60 |
| neurodegeneration | activates | disease | 0.60 |
| CD68 | expressed_in | gene | 0.60 |
| TYROBP | expressed_in | gene | 0.60 |
| CD86 | expressed_in | gene | 0.60 |
| NLRP3 | expressed_in | gene | 0.60 |
| PI3K | inhibits | gene | 0.60 |
| CD38 | activates | gene | 0.60 |
| CD36 | biomarker_for | gene | 0.60 |
| GPX4 | biomarker_for | gene | 0.60 |
| HO1 | biomarker_for | gene | 0.60 |
| IL6 | biomarker_for | gene | 0.60 |
| LRP1 | biomarker_for | gene | 0.60 |
| SLC40A1 | biomarker_for | gene | 0.60 |
| SLC7A11 | biomarker_for | gene | 0.60 |
| TNF | biomarker_for | gene | 0.60 |
| ferroptosis | participates_in | pathway | 0.60 |
| oxidative stress response | participates_in | pathway | 0.60 |
| JAK-STAT signaling | participates_in | pathway | 0.60 |
| NF-kB signaling | participates_in | pathway | 0.60 |
| Alzheimer's disease | biomarker_for | disease | 0.60 |
| METTL3 | activates | gene | 0.60 |
| YTHDF1 | activates | gene | 0.60 |
| TGF | activates | gene | 0.60 |
| TGF-beta signaling | participates_in | pathway | 0.60 |
| MAPK | activates | gene | 0.60 |
| PI3K-AKT-mTOR signaling | participates_in | pathway | 0.60 |
| MAPK signaling | participates_in | pathway | 0.60 |
| GSH | biomarker_for | gene | 0.60 |
| microglia | expressed_in | cell_type | 0.55 |
| macrophages | expressed_in | cell_type | 0.55 |
| benchmark_ot_ad_answer_key:CD206 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PPARγ antagonist | activates | drug | 0.70 |
| ARG1 | activates | gene | 0.60 |
| CD163 | activates | gene | 0.60 |
| CD14 | associated_with | gene | 0.60 |
| CD163 | associated_with | gene | 0.60 |
| ASC | biomarker_for | gene | 0.60 |
| ACSL4 | biomarker_for | gene | 0.60 |
| CD163 | biomarker_for | gene | 0.60 |
| AMPK | activates | gene | 0.60 |
| benchmark_ot_ad_answer_key:CD206 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||