Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DOPAMINE RECEPTOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal Uptake | mediates | process | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| DRD2 | regulates | gene | 0.80 |
| Parkinson's disease | involves | disease | 0.80 |
| NLRP3 | activates | gene | 0.70 |
| DRD2 | interacts_with | gene | 0.70 |
| depression | involves | disease | 0.70 |
| schizophrenia | involves | disease | 0.70 |
| neurodegeneration | involves | disease | 0.70 |
| DRD2 | activates | gene | 0.70 |
| DRD2 | inhibits | gene | 0.70 |
| DRD2 | transported_by | gene | 0.70 |
| ALOX15 | regulates | gene | 0.60 |
| LOX | regulates | gene | 0.60 |
| ALOX15 | protects_against | gene | 0.60 |
| LOX | protects_against | gene | 0.60 |
| levodopa | treats | compound | 0.60 |
| berberine | regulates | compound | 0.60 |
| ERN1 | activates | gene | 0.60 |
| ULK1 | activates | gene | 0.60 |
| BECN1 | activates | gene | 0.60 |
| ASC | activates | gene | 0.60 |
| TNF | activates | gene | 0.60 |
| RIPK3 | activates | gene | 0.60 |
| TNFA | activates | gene | 0.60 |
| STAT3 | activates | gene | 0.60 |
| PYCARD | activates | gene | 0.60 |
| PI3K | activates | gene | 0.60 |
| MTOR | activates | gene | 0.60 |
| SQSTM1 | activates | gene | 0.60 |
| LC3 | activates | gene | 0.60 |
| ERN1 | regulates | gene | 0.60 |
| NLRP3 | regulates | gene | 0.60 |
| ULK1 | regulates | gene | 0.60 |
| BECN1 | regulates | gene | 0.60 |
| ASC | regulates | gene | 0.60 |
| TNF | regulates | gene | 0.60 |
| RIPK3 | regulates | gene | 0.60 |
| TNFA | regulates | gene | 0.60 |
| STAT3 | regulates | gene | 0.60 |
| PYCARD | regulates | gene | 0.60 |
| PI3K | regulates | gene | 0.60 |
| MTOR | regulates | gene | 0.60 |
| SQSTM1 | regulates | gene | 0.60 |
| LC3 | regulates | gene | 0.60 |
| DRD2 | associated_with | gene | 0.60 |
| levodopa | activates | compound | 0.60 |
| levodopa | inhibits | compound | 0.60 |
| NLRP3 | interacts_with | gene | 0.60 |
| TREM2 | activates | gene | 0.60 |
| TREM2 | inhibits | gene | 0.60 |
| GABRA1 | transported_by | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||