concept

GABAERGIC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GABAERGIC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

85Connections

0Hypotheses

0Analyses

50Outgoing

22Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	GABAERGIC
Key Genes/Proteins	AMPK
Linked Hypotheses	3 hypotheses

Wiki Pages (20)

Knowledge base pages for this entity

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

therapeutic · 15567 words

→

Pathway Diagram

graph TD
    GABAERGIC["GABAERGIC"]
    GABAERGIC -->|"inhibits"| GLUTAMATERGIC["GLUTAMATERGIC"]
    GABAERGIC -->|"inhibits"| NEURON["NEURON"]
    GABAERGIC -->|"inhibits"| NEURONS["NEURONS"]
    GABAERGIC -->|"inhibits"| NEUROTRANSMISSION["NEUROTRANSMISSION"]
    GABAERGIC -.protects against.-> MICROGLIA["MICROGLIA"]
    GABAERGIC -->|"targets"| INTERNEURON["INTERNEURON"]
    CA1["CA1"] -->|"inhibits"| GABAERGIC
    DOPAMINERGIC["DOPAMINERGIC"] -->|"regulates"| GABAERGIC
    CORTEX["CORTEX"] -->|"targets"| GABAERGIC
    ALZHEIMER["ALZHEIMER"] -.protects against.-> GABAERGIC
    ALZHEIMER_S["ALZHEIMER'S"] -.protects against.-> GABAERGIC
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -.protects against.-> GABAERGIC
    AMYLOID["AMYLOID"] -->|"targets"| GABAERGIC

Outgoing (56)

Target	Relation	Type	Str
GLUTAMATERGIC	inhibits	cell_type	0.65
NEURON	inhibits	cell_type	0.65
NEURONS	inhibits	cell_type	0.65
NEURON	protects_against	cell_type	0.65
NEURONS	protects_against	cell_type	0.65
RAPAMYCIN	regulates	drug	0.65
INTERNEURON	inhibits	cell_type	0.65
INTERNEURON	biomarker_for	cell_type	0.65
NEURON	contributes_to	cell_type	0.65
NEURON	causes	cell_type	0.65
NEURONS	causes	cell_type	0.65
MICROGLIA	protects_against	cell_type	0.60
NEURON	targets	cell_type	0.60
NEURONS	targets	cell_type	0.60
INTERNEURON	targets	cell_type	0.60
INTERNEURONS	targets	cell_type	0.60
INTERNEURON	activates	cell_type	0.60
INTERNEURONS	activates	cell_type	0.60
NEURON	activates	cell_type	0.60
NEURONS	activates	cell_type	0.60
MTOR	regulates	gene	0.60
MICROGLIA	activates	cell_type	0.60
GLUTAMATERGIC	biomarker_for	cell_type	0.60
HIPPOCAMPUS	biomarker_for	brain_region	0.60
GLUTAMATERGIC	associated_with	cell_type	0.60
NEURON	associated_with	cell_type	0.60
NEURONS	associated_with	cell_type	0.60
NEURON	regulates	cell_type	0.60
NEURON	expressed_in	cell_type	0.60
NEURONS	promotes	cell_type	0.60
INTERNEURON	expressed_in	cell_type	0.60
INTERNEURONS	expressed_in	cell_type	0.60
NEURODEGENERATION	biomarker_for	disease	0.60
NEURON	biomarker_for	cell_type	0.60
NEURONS	biomarker_for	cell_type	0.60
INTERNEURON	associated_with	cell_type	0.60
INTERNEURONS	associated_with	cell_type	0.60
PURKINJE	associated_with	cell_type	0.60
INTERNEURON	contributes_to	cell_type	0.60
T CELL	contributes_to	cell_type	0.60
NEURONS	expressed_in	cell_type	0.60
GLUTAMATERGIC	targets	cell_type	0.60
GLUTAMATERGIC	co_discussed	cell_type	0.40
T CELL	co_discussed	cell_type	0.40
T CELLS	co_discussed	cell_type	0.40
GABRA1	co_discussed	gene	0.40
GRIA1	co_discussed	gene	0.40
HTR2A	co_discussed	gene	0.40
SEROTONERGIC	co_discussed	cell_type	0.40
STRIATUM	co_discussed	brain_region	0.40

Incoming (29)

Source	Relation	Type	Str
CA1	inhibits	brain_region	0.65
DOPAMINERGIC	regulates	cell_type	0.65
CORTEX	targets	brain_region	0.65
AMPK	associated_with	gene	0.65
DOPAMINERGIC	inhibits	cell_type	0.60
ALZHEIMER	protects_against	disease	0.60
ALZHEIMER'S	protects_against	disease	0.60
ALZHEIMER'S DISEASE	protects_against	disease	0.60
APP	targets	gene	0.60
CORTEX	activates	brain_region	0.60
CHOLINERGIC	biomarker_for	cell_type	0.60
ALZHEIMER	expressed_in	disease	0.60
ALZHEIMER'S	expressed_in	disease	0.60
ALZHEIMER'S DISEASE	expressed_in	disease	0.60
CORTEX	biomarker_for	brain_region	0.60
CEREBELLUM	promotes	brain_region	0.60
ASTROCYTE	contributes_to	cell_type	0.60
ASTROCYTES	contributes_to	cell_type	0.60
DEPRESSION	inhibits	disease	0.60
DRD1	co_discussed	gene	0.40
DRD2	co_discussed	gene	0.40
DEPRESSION	co_discussed	disease	0.40

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

GABAERGIC

Understanding Entity Pages

Wiki Pages (20)

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

Progressive Supranuclear Palsy (PSP)

Novel Therapy Index

Atypical Parkinsonism

calcium-dysregulation-comparison

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

Myoclonus and Cortical Hyperexcitability in Corticobasal Syndrome

PD Combination Therapy Matrix

Therapeutics

NPM1 Gene

Neurons — Cell Type Hierarchy

Frontotemporal Dementia (FTD) Mechanistic Pathway

CBS/PSP Treatment Rankings

NTF4 Protein

Neuroimmune Response in 4R-Tauopathies: Cross-Disease Comparison

GSK-3β in Neurodegeneration

CNTN5 — Contactin 5

Growth Factor Therapies