CTSL

Understanding Entity Pages

This page aggregates everything SciDEX knows about CTSL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CTSL is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, therapeutic target. Associated with Aging, Als, Alzheimer. Connected to 62 entities in the SciDEX knowledge graph.

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graph TD
    CTSL["<b>CTSL</b>"]
    Als{"Als"}
    CTSL -->|"therapeutic target"| Als
    Cancer{"Cancer"}
    CTSL -->|"therapeutic target"| Cancer
    Tumor{"Tumor"}
    CTSL -->|"therapeutic target"| Tumor
    Alzheimer{"Alzheimer"}
    CTSL -->|"activates"| Alzheimer
    Aging{"Aging"}
    CTSL -->|"activates"| Aging
    Neuroinflammation{"Neuroinflammation"}
    CTSL -->|"activates"| Neuroinflammation
    Inflammation{"Inflammation"}
    CTSL -->|"activates"| Inflammation
    FOXO3["FOXO3"]
    CTSL -->|"therapeutic target"| FOXO3
    BCL2_FAMILY["BCL2 FAMILY"]
    CTSL -->|"regulates"| BCL2_FAMILY
    CANCER["CANCER"]
    CTSL -->|"therapeutic target"| CANCER
    AUTOPHAGY["AUTOPHAGY"]
    CTSL -->|"regulates"| AUTOPHAGY
    OXIDATIVE_STRESS["OXIDATIVE STRESS"]
    CTSL -->|"therapeutic target"| OXIDATIVE_STRESS
    BNIP3["BNIP3"]
    BNIP3 -->|"regulates"| CTSL
    BCL2["BCL2"]
    BCL2 -->|"regulates"| CTSL
    AGING["AGING"]
    AGING -->|"activates"| CTSL
    CTSB["CTSB"]
    CTSB -->|"activates"| CTSL
    MICROGLIA_ACTIVATION["MICROGLIA ACTIVATION"]
    MICROGLIA_ACTIVATION -->|"activates"| CTSL
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"activates"| CTSL
    style CTSL fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0