KCNQ2

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNQ2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

KCNQ2 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, regulates, activates. Associated with Aging, Als, Autism. Connected to 44 entities in the SciDEX knowledge graph.

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graph TD
    KCNQ2["<b>KCNQ2</b>"]
    Aging{"Aging"}
    KCNQ2 -->|"therapeutic target"| Aging
    Als{"Als"}
    KCNQ2 -->|"therapeutic target"| Als
    Neuroinflammation{"Neuroinflammation"}
    KCNQ2 -->|"therapeutic target"| Neuroinflammation
    Epilepsy{"Epilepsy"}
    KCNQ2 -->|"therapeutic target"| Epilepsy
    Autism{"Autism"}
    KCNQ2 -->|"therapeutic target"| Autism
    Ms{"Ms"}
    KCNQ2 -->|"therapeutic target"| Ms
    Inflammation{"Inflammation"}
    KCNQ2 -->|"therapeutic target"| Inflammation
    KCNQ2 -->|"regulates"| Als
    Tumor{"Tumor"}
    KCNQ2 -->|"activates"| Tumor
    KCNQ2 -->|"regulates"| Ms
    Cancer{"Cancer"}
    KCNQ2 -->|"activates"| Cancer
    KCNQ2 -->|"expressed in"| Ms
    DHX9["DHX9"]
    DHX9 -->|"therapeutic target"| KCNQ2
    KCNT1["KCNT1"]
    KCNT1 -->|"associated with"| KCNQ2
    KCNQ3["KCNQ3"]
    KCNQ3 -->|"regulates"| KCNQ2
    EGFR["EGFR"]
    EGFR -->|"activates"| KCNQ2
    ERK["ERK"]
    ERK -->|"activates"| KCNQ2
    HDAC2["HDAC2"]
    HDAC2 -->|"regulates"| KCNQ2
    MECP2["MECP2"]
    MECP2 -->|"regulates"| KCNQ2
    CANCER["CANCER"]
    CANCER -->|"activates"| KCNQ2
    style KCNQ2 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0