concept

HOMOLOGOUS RECOMBINATION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HOMOLOGOUS RECOMBINATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

88Connections

0Hypotheses

0Analyses

2Outgoing

36Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	HOMOLOGOUS RECOMBINATION
Key Genes/Proteins	CGAS, TFEB, ACTB, ULK1, SETX, BECN1
Related Diseases	cancer, Ovarian Cancer

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    HOMOLOGOUS_RECOMBINATION["HOMOLOGOUS RECOMBINATION"]
    CANCER["CANCER"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    Cancer["Cancer"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    SQSTM1["SQSTM1"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    PI3K["PI3K"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    BRCA1["BRCA1"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    RAS["RAS"] -->|"inhibits"| HOMOLOGOUS_RECOMBINATION
    NRF2["NRF2"] -->|"target for"| HOMOLOGOUS_RECOMBINATION
    P62["P62"] -->|"target for"| HOMOLOGOUS_RECOMBINATION

Outgoing (6)

Target	Relation	Type	Str
RAPAMYCIN	activates	concept	0.50
RAPAMYCIN	associated_with	drug	0.45

Incoming (82)

Source	Relation	Type	Str
CGAS	inhibits	protein	0.50
cancer	inhibits	disease	0.50
Ovarian Cancer	inhibits	disease	0.50
TFEB	activates	protein	0.50
ACTB	activates	gene	0.50
Autophagy	activates	process	0.50
ULK1	activates	gene	0.50
SETX	activates	gene	0.50
BECN1	activates	gene	0.50
GABA	activates	gene	0.50
SQSTM1	activates	gene	0.50
SMN1	activates	gene	0.50
WIPI2	activates	gene	0.50
ALS4	activates	gene	0.50
ATG7	activates	protein	0.50
GABARAP	activates	protein	0.50
CHIP	activates	protein	0.50
HUNTINGTIN	activates	protein	0.50
DNMT1	activates	protein	0.50
DEMENTIA	activates	gene	0.50
amyotrophic lateral sclerosis	activates	gene	0.50
MAP1LC3	activates	gene	0.50
FRONTOTEMPORAL DEMENTIA	activates	disease	0.50
MTORC1	activates	concept	0.50
Ataxia	activates	disease	0.50
Neuron	activates	cell_type	0.50
Spinocerebellar Ataxia	activates	disease	0.50
FRONTOTEMPORAL	activates	concept	0.50
DNA DAMAGE	activates	concept	0.50
MOTOR NEURON	activates	concept	0.50
Dna Damage Response	activates	pathway	0.50
RAD51	activates	gene	0.50
STAT6	activates	gene	0.50
Dna Repair	activates	pathway	0.50
AQP4	associated_with	gene	0.50
CHLOROQUINE	associated_with	drug	0.45

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

HOMOLOGOUS RECOMBINATION

Understanding Entity Pages

Wiki Pages (20)

Parthanatos in Neurodegeneration

Non-Homologous End Joining in Neurodegeneration

DNA Damage Response in Parkinson's Disease

DNA Damage Response in Corticobasal Syndrome

DNA Damage Response Impairment Pathway

gba

dna-damage-repair

DNA Damage Response in Alzheimer's Disease

Ataxin-3 (Josephin)

ataxia-telangiectasia

RAD21 — Cohesin Complex Component in Neurodegeneration

atxn3-protein

POLN Gene — DNA Polymerase Nu

TERT Gene

DNA Damage Response in Corticobasal Syndrome

H3F3B Gene — H3.3 Histone B

DOT1L Gene

setd1a