P75NTR

Understanding Entity Pages

This page aggregates everything SciDEX knows about P75NTR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

P75NTR is a gene implicated in neurodegeneration research. Key relationships include: activates, interacts with, associated with. Associated with ALS, Als, Alzheimer. Connected to 105 entities in the SciDEX knowledge graph.

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graph TD
    P75NTR["<b>P75NTR</b>"]
    NEUROTROPHINS["NEUROTROPHINS"]
    P75NTR -->|"interacts with"| NEUROTROPHINS
    Amyotrophic_Lateral_Sclerosis{"Amyotrophic Lateral Sclerosis"}
    P75NTR -->|"interacts with"| Amyotrophic_Lateral_Sclerosis
    Neurodegeneration{"Neurodegeneration"}
    P75NTR -->|"interacts with"| Neurodegeneration
    Als{"Als"}
    P75NTR -->|"interacts with"| Als
    Alzheimer{"Alzheimer"}
    P75NTR -->|"interacts with"| Alzheimer
    Parkinson{"Parkinson"}
    P75NTR -->|"interacts with"| Parkinson
    Huntington{"Huntington"}
    P75NTR -->|"interacts with"| Huntington
    Neuropathy{"Neuropathy"}
    P75NTR -->|"interacts with"| Neuropathy
    P75NTR -->|"inhibits"| Alzheimer
    P75NTR -->|"inhibits"| Amyotrophic_Lateral_Sclerosis
    P75NTR -->|"inhibits"| Huntington
    P75NTR -->|"inhibits"| Neurodegeneration
    PROBDNF["PROBDNF"]
    PROBDNF -->|"activates"| P75NTR
    BAX["BAX"]
    BAX -->|"activates"| P75NTR
    PI3K["PI3K"]
    PI3K -->|"activates"| P75NTR
    CYTOKINES["CYTOKINES"]
    CYTOKINES -->|"activates"| P75NTR
    AKT["AKT"]
    AKT -->|"activates"| P75NTR
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"interacts with"| P75NTR
    NEURODEGENERATIVE_DISEASES["NEURODEGENERATIVE DISEASES"]
    NEURODEGENERATIVE_DISEASES -->|"interacts with"| P75NTR
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"interacts with"| P75NTR
    ALS["ALS"]
    ALS -->|"interacts with"| P75NTR
    PARKINSON_S_DISEASE["PARKINSON'S DISEASE"]
    PARKINSON_S_DISEASE -->|"interacts with"| P75NTR
    PARKINSON["PARKINSON"]
    PARKINSON -->|"interacts with"| P75NTR
    NEURODEGENERATION["NEURODEGENERATION"]
    NEURODEGENERATION -->|"interacts with"| P75NTR
    style P75NTR fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0