DRD4

Understanding Entity Pages

This page aggregates everything SciDEX knows about DRD4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DRD4 is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, expressed in. Associated with Als, Cancer, Ms. Connected to 33 entities in the SciDEX knowledge graph.

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graph TD
    DRD4["<b>DRD4</b>"]
    Als{"Als"}
    DRD4 -->|"therapeutic target"| Als
    Ms{"Ms"}
    DRD4 -->|"therapeutic target"| Ms
    Cancer{"Cancer"}
    DRD4 -->|"therapeutic target"| Cancer
    Tumor{"Tumor"}
    DRD4 -->|"therapeutic target"| Tumor
    SUD{"SUD"}
    DRD4 -->|"associated with"| SUD
    OPRM1["OPRM1"]
    DRD4 -->|"associated with"| OPRM1
    BDNF["BDNF"]
    DRD4 -->|"associated with"| BDNF
    SLC6A4["SLC6A4"]
    DRD4 -->|"associated with"| SLC6A4
    OVERVIEW["OVERVIEW"]
    DRD4 -->|"associated with"| OVERVIEW
    DRD2["DRD2"]
    DRD4 -->|"associated with"| DRD2
    ULK3["ULK3"]
    DRD4 -->|"expressed in"| ULK3
    DDIT3["DDIT3"]
    DRD4 -->|"expressed in"| DDIT3
    DRD2 -->|"associated with"| DRD4
    CHRNA5["CHRNA5"]
    CHRNA5 -->|"associated with"| DRD4
    FOXP2["FOXP2"]
    FOXP2 -->|"associated with"| DRD4
    ADH1B["ADH1B"]
    ADH1B -->|"associated with"| DRD4
    BDNF -->|"associated with"| DRD4
    GENES["GENES"]
    GENES -->|"associated with"| DRD4
    TP53["TP53"]
    TP53 -->|"therapeutic target"| DRD4
    SRC["SRC"]
    SRC -->|"therapeutic target"| DRD4
    PI3K["PI3K"]
    PI3K -->|"therapeutic target"| DRD4
    AKT["AKT"]
    AKT -->|"therapeutic target"| DRD4
    AKT1["AKT1"]
    AKT1 -->|"therapeutic target"| DRD4
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"therapeutic target"| DRD4
    style DRD4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0