concept

EPITHELIAL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EPITHELIAL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

655Connections

0Hypotheses

0Analyses

4Outgoing

50Incoming

0Experiments

0Debates

No summary available yet.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	EPITHELIAL

Pathway Diagram

graph TD
    EPITHELIAL["EPITHELIAL"]
    style EPITHELIAL fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    EPITHELIAL -->|"expressed in"| Basal_Ganglia((Basal Ganglia))
    EPITHELIAL -->|"expressed in"| Gray_Matter((Gray Matter))
    EPITHELIAL -->|"expressed in"| Brainstem((Brainstem))
    EPITHELIAL -->|"expressed in"| Substantia_Nigra((Substantia Nigra))
    CPT1A([CPT1A]) -->|"regulates"| EPITHELIAL
    MITOCHONDRIA([MITOCHONDRIA]) -->|"activates"| EPITHELIAL
    SQSTM1([SQSTM1]) -->|"regulates"| EPITHELIAL
    PPARG([PPARG]) -->|"regulates"| EPITHELIAL
    RPS6KB1([RPS6KB1]) -->|"regulates"| EPITHELIAL
    LRP2([LRP2]) -->|"regulates"| EPITHELIAL
    NADH([NADH]) -->|"regulates"| EPITHELIAL
    ATG([ATG]) -->|"regulates"| EPITHELIAL
    PPARA([PPARA]) -->|"regulates"| EPITHELIAL
    EIF4EBP1([EIF4EBP1]) -->|"regulates"| EPITHELIAL

Outgoing (4)

Target	Relation	Type	Str
Basal Ganglia	expressed_in	brain_region	0.50
Gray Matter	expressed_in	brain_region	0.50
Substantia Nigra	expressed_in	brain_region	0.50
Brainstem	expressed_in	brain_region	0.50

Incoming (651)

Source	Relation	Type	Str
SQSTM1	associated_with	gene	0.60
APOPTOSIS	activates	gene	0.60
IL-17	activates	gene	0.60
S100A9	activates	gene	0.60
BAX	activates	gene	0.60
S100A8	activates	gene	0.60
DIO2	activates	gene	0.60
PPARGC1A	activates	gene	0.60
CXCL10	expressed_in	gene	0.60
CXCR3	expressed_in	gene	0.60
LRP1	expressed_in	gene	0.60
PD-L1	therapeutic_target	gene	0.60
PD-1	therapeutic_target	gene	0.60
LRP1	contributes_to	gene	0.60
TNF	inhibits	gene	0.60
EFHD2	inhibits	gene	0.60
TNFR1	inhibits	gene	0.60
COFILIN	inhibits	gene	0.60
PINK1	activates	gene	0.60
AKT	activates	gene	0.60
FERROPTOSIS	therapeutic_target	gene	0.60
MTOR	associated_with	gene	0.60
STAT3	associated_with	gene	0.60
ROS	associated_with	gene	0.60
MMP9	activates	gene	0.60
RIPK3	associated_with	gene	0.60
NOD2	associated_with	gene	0.60
NLR	associated_with	gene	0.60
NLRP3	associated_with	gene	0.60
NRBF2	associated_with	gene	0.60
PI3K	associated_with	gene	0.60
BECN1	associated_with	gene	0.60
MAPK	associated_with	gene	0.60
MELK	associated_with	gene	0.60
ATG	associated_with	gene	0.60
BECLIN1	associated_with	gene	0.60
MTNR1A	expressed_in	gene	0.60
CAV1	activates	gene	0.60
SCD1	activates	gene	0.60
HMGCR	activates	gene	0.60
PD-L1	activates	gene	0.60
FASN	activates	gene	0.60
PD-1	activates	gene	0.60
SIRT1	inhibits	gene	0.60
FOXO1	inhibits	gene	0.60
ROS	inhibits	gene	0.60
ERK	inhibits	gene	0.60
AUTOPHAGY	inhibits	gene	0.60
GAPDH	inhibits	gene	0.60
P53	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EPITHELIAL in their description or question text

No additional research found