concept

MAST CELL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAST CELL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

123Connections

0Hypotheses

0Analyses

22Outgoing

7Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	MAST CELL
Related Diseases	STROKE

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    MAST_CELL["MAST CELL"]
    MAST_CELL -->|"causes"| STROKE["STROKE"]
    MAST_CELL -->|"causes"| T_CELL["T CELL"]
    MAST_CELL -->|"activates"| T_CELLS["T CELLS"]
    MAST_CELL -->|"contributes to"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
    MAST_CELL -->|"contributes to"| NEURON["NEURON"]
    STROKE -->|"activates"| MAST_CELL
    IL_33["IL-33"] -->|"activates"| MAST_CELL
    TSLP["TSLP"] -->|"activates"| MAST_CELL
    CYTOKINES["CYTOKINES"] -->|"target for"| MAST_CELL
    ALZHEIMER["ALZHEIMER"] -->|"activates"| MAST_CELL
    CRH["CRH"] -->|"activates"| MAST_CELL
    AMYLOID["AMYLOID"] -->|"activates"| MAST_CELL
    PARKINSON["PARKINSON"] -->|"activates"| MAST_CELL

Outgoing (24)

Target	Relation	Type	Str
NEURON	activates	cell_type	0.65
NEUTROPHIL	contributes_to	cell_type	0.65
T CELL	contributes_to	cell_type	0.65
STROKE	causes	disease	0.60
T CELL	causes	cell_type	0.60
STROKE	activates	disease	0.60
T CELL	activates	cell_type	0.60
T CELLS	activates	cell_type	0.60
NEURON	contributes_to	cell_type	0.60
T CELLS	causes	cell_type	0.60
T CELL	associated_with	cell_type	0.60
T CELLS	associated_with	cell_type	0.60
T CELL	targets	cell_type	0.60
T CELLS	targets	cell_type	0.60
T CELL	expressed_in	cell_type	0.60
T CELLS	expressed_in	cell_type	0.60
NEURODEGENERATION	associated_with	disease	0.60
T CELL	co_discussed	cell_type	0.40
T CELLS	co_discussed	cell_type	0.40
MICROGLIA	co_discussed	cell_type	0.40
THALAMUS	co_discussed	brain_region	0.40
NEUTROPHIL	co_discussed	cell_type	0.40

Incoming (99)

Source	Relation	Type	Str
MACROPHAGE	contributes_to	cell_type	0.65
ACHE	activates	gene	0.60
ALZHEIMER'S	expressed_in	disease	0.60
HYPOTHALAMUS	co_discussed	brain_region	0.40
FGF	co_discussed	gene	0.40
MACROPHAGE	co_discussed	cell_type	0.40
MACROPHAGES	co_discussed	cell_type	0.40

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

MAST CELL

Understanding Entity Pages

Wiki Pages (20)

Histamine

AD Therapeutic Approaches Ranked Scorecard

MS4A4A Gene — Membrane-Spanning 4-Domains A4A

SERPINA3 Gene — Alpha-1 Antichymotrypsin in Neurodegeneration

AD Combination Therapy Matrix

IL3 (Interleukin 3)

TYROBP/DAP12 Microglia Signaling Pathway in Alzheimer's Disease

Amyotrophic Lateral Sclerosis (ALS) Treatment

AB Science

SLC18A2 Gene

Purinergic Signaling in Parkinson's Disease

GAB2 — GRB2 Associated Binding Protein 2

Phase 3 Study to Compare the Efficacy and Safety of Masitini... (NCT03127267)

slc17a9

SLC30A5 — Solute Carrier Family 3 Member 0A5 (SLC30A5)

IL25 (Interleukin 25)

Peripheral Immune System in Parkinson's Disease

Triggering Receptor Expressed on Myeloid Cells 3 (TREM3)