Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Camp Signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | Camp Signaling |
| Category | kind:mechanism, section:mechanisms, state:published |
| Summary | Page for cAMP Signaling Pathway in Neurodegeneration |
| Key Genes/Proteins | RGS6, AKT, PI3K, NEURON, PARKINSON, NEURODEGENERATION |
| Related Diseases | Als, Parkinson |
Knowledge base pages for this entity
graph TD
Als["Als"] -->|"therapeutic target"| Camp_Signaling["Camp Signaling"]
RGS6["RGS6"] -.->|"inhibits"| Camp_Signaling["Camp Signaling"]
AKT["AKT"] -->|"protects against"| Camp_Signaling["Camp Signaling"]
PI3K["PI3K"] -->|"protects against"| Camp_Signaling["Camp Signaling"]
style Camp_Signaling fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| DOPAMINE | inhibits | concept | 0.50 |
| MAPK SIGNALING | protects_against | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Als | therapeutic_target | disease | 0.65 |
| RGS6 | inhibits | gene | 0.60 |
| AKT | protects_against | gene | 0.60 |
| PI3K | protects_against | gene | 0.60 |
| NEURON | inhibits | gene | 0.60 |
| PARKINSON | inhibits | gene | 0.60 |
| NEURODEGENERATION | inhibits | gene | 0.60 |
| APOPTOSIS | inhibits | gene | 0.60 |
| STROKE | inhibits | gene | 0.60 |
| PARKINSON'S DISEASE | therapeutic_target | gene | 0.60 |
| OXIDATIVE STRESS | therapeutic_target | gene | 0.60 |
| PARKINSON | therapeutic_target | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | associated_with | gene | 0.60 |
| FERROPTOSIS | therapeutic_target | gene | 0.60 |
| Parkinson | therapeutic_target | disease | 0.60 |
| ERK1 | treats | gene | 0.60 |
| RAF1 | treats | gene | 0.60 |
| ANXIETY | treats | gene | 0.60 |
| BDNF | treats | gene | 0.60 |
| CREB1 | treats | gene | 0.60 |
| DEPRESSION | therapeutic_target | gene | 0.60 |
| SYNAPSE | therapeutic_target | gene | 0.60 |
| Anxiety | treats | disease | 0.60 |
| Depression | therapeutic_target | disease | 0.60 |
| CREB | inhibits | gene | 0.60 |
| APOPTOSIS | regulates | gene | 0.60 |
| APP/PS1 | inhibits | gene | 0.60 |
| BDNF | inhibits | gene | 0.60 |
| ALZHEIMER | inhibits | gene | 0.60 |
| PDE4B | inhibits | gene | 0.60 |
| ALZHEIMER'S DISEASE | inhibits | gene | 0.60 |
| BCL-2 | inhibits | gene | 0.60 |
| APP | inhibits | gene | 0.60 |
| DEMENTIA | inhibits | gene | 0.60 |
| Dementia | inhibits | disease | 0.60 |
| Als | inhibits | disease | 0.60 |
| Alzheimer | inhibits | disease | 0.60 |
| AND | regulates | gene | 0.60 |
| PAK1 | regulates | gene | 0.60 |
| CIRCADIAN RHYTHM | regulates | gene | 0.60 |
| BMAL1 | regulates | gene | 0.60 |
| ATG5 | regulates | gene | 0.60 |
| P21 | regulates | gene | 0.60 |
| LC3 | regulates | gene | 0.60 |
| DEPRESSION | regulates | gene | 0.60 |
| ATG7 | regulates | gene | 0.60 |
| P62 | regulates | gene | 0.60 |
| CREB | regulates | gene | 0.60 |
| AUTOPHAGY | regulates | gene | 0.60 |
| TP53 | therapeutic_target | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||