concept

GLP1R

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GLP1R: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

354Connections
0Hypotheses
1Analyses
50Outgoing
50Incoming

Summary

GLP1R is a concept in neurodegeneration research. Key relationships include: interacts with, inhibits, expressed in. Associated with ALS, Als, Hepatitis. Connected to 93 entities in the SciDEX knowledge graph.

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💡 Concept Info
NameGLP1R
Key Genes/ProteinsBDNF, GFRAL, GDNF, SREBF1
Related DiseasesAls, Tumor, Hepatitis, ALS, Alzheimer
🧬 3D Structure: GLP1R — PDB 6X18 Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

Device Therapies Comparison for CBS/PSP

therapeutic · 6867 words

Section 148: Advanced Nutritional Biochemistry in CBS/PSP

therapeutic · 6350 words

CBS/PSP Treatment Rankings

therapeutic · 5434 words

Pathway Diagram

graph TD
    GLP1R["GLP1R"]
    GLP1R -->|"inhibits"| Als["Als"]
    GLP1R -->|"interacts"| Tumor["Tumor"]
    GLP1R -->|"interacts"| Hepatitis["Hepatitis"]
    GLP1R -->|"inhibits"| ALS["ALS"]
    GLP1R -->|"interacts"| BDNF["BDNF"]
    GLP1R -->|"inhibits"| GFRAL["GFRAL"]
    GLP1R -->|"inhibits"| GDNF["GDNF"]
    GLP1R -->|"interacts"| SREBF1["SREBF1"]
    GLP1R -->|"interacts"| SIRT1["SIRT1"]
    h_ee1df336["h-ee1df336"] -->|"targets"| GLP1R
    BDNF -->|"interacts"| GLP1R
    PPARA["PPARA"] -->|"interacts"| GLP1R
    ULK1["ULK1"] -->|"interacts"| GLP1R
    STX17["STX17"] -->|"interacts"| GLP1R
    SQSTM1["SQSTM1"] -->|"interacts"| GLP1R
    NOS3["NOS3"] -->|"interacts"| GLP1R
    STING1["STING1"] -->|"interacts"| GLP1R
    GDNF -->|"inhibits"| GLP1R

Outgoing (209)

TargetRelationTypeStr
BDNF neuronsregulatescell_type0.80
NLY01activatesdrug0.80
Alsinhibitsdisease0.65
Tumorinteracts_withdisease0.65
Hepatitisinteracts_withdisease0.65

Incoming (145)

SourceRelationTypeStr
h-ee1df336targets_genehypothesis0.90
h-ee1df336targetshypothesis0.80
BDNFinteracts_withgene0.62
BDNFinhibitsgene0.60
PPARAinteracts_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

What are the mechanisms by which gut microbiome dysbiosis influences Parkinson's

neurodegeneration | 2026-04-01 | 20 hypotheses Top: 0.617

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found