GUSB

Understanding Entity Pages

This page aggregates everything SciDEX knows about GUSB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GUSB is a gene implicated in neurodegeneration research. Key relationships include: associated with, therapeutic target, implicated in. Associated with Aging, Als, Cancer. Connected to 33 entities in the SciDEX knowledge graph.

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graph TD
    GUSB["<b>GUSB</b>"]
    Diabetes{"Diabetes"}
    GUSB -->|"associated with"| Diabetes
    Als{"Als"}
    GUSB -->|"associated with"| Als
    Aging{"Aging"}
    GUSB -->|"associated with"| Aging
    Ms{"Ms"}
    GUSB -->|"associated with"| Ms
    Cancer{"Cancer"}
    GUSB -->|"associated with"| Cancer
    Inflammation{"Inflammation"}
    GUSB -->|"associated with"| Inflammation
    Complement(["Complement"])
    GUSB -->|"associated with"| Complement
    FGF21["FGF21"]
    GUSB -->|"associated with"| FGF21
    ALDH1A1["ALDH1A1"]
    GUSB -->|"therapeutic target"| ALDH1A1
    LPL["LPL"]
    GUSB -->|"therapeutic target"| LPL
    HMOX1["HMOX1"]
    GUSB -->|"associated with"| HMOX1
    CTSD["CTSD"]
    GUSB -->|"associated with"| CTSD
    FGF21 -->|"associated with"| GUSB
    HMOX1 -->|"associated with"| GUSB
    ALDH1A1 -->|"therapeutic target"| GUSB
    CTSD -->|"associated with"| GUSB
    LPL -->|"therapeutic target"| GUSB
    HDAC6["HDAC6"]
    HDAC6 -->|"associated with"| GUSB
    TP53["TP53"]
    TP53 -->|"associated with"| GUSB
    CCT2["CCT2"]
    CCT2 -->|"associated with"| GUSB
    style GUSB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0