concept

PURKINJE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PURKINJE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

87Connections
0Hypotheses
0Analyses
1Outgoing
20Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NamePURKINJE
Key Genes/ProteinsSTING, C9ORF72
Related DiseasesATAXIA

Wiki Pages (20)

Knowledge base pages for this entity

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

Novel Therapy Index

idea · 10647 words

calcium-dysregulation-comparison

mechanism · 6468 words

NPM1 Gene

gene · 5653 words

Neurons — Cell Type Hierarchy

cell · 5551 words

Pathway Diagram

graph TD
    PURKINJE["PURKINJE"]
    PURKINJE -->|"interacts"| STING["STING"]
    PURKINJE -->|"expressed in"| Thalamus["Thalamus"]
    PURKINJE -->|"expressed in"| Substantia_Nigra["Substantia Nigra"]
    PURKINJE -->|"expressed in"| Hypothalamus["Hypothalamus"]
    PURKINJE -->|"expressed in"| Cerebellum["Cerebellum"]
    PURKINJE -->|"expressed in"| Hippocampus["Hippocampus"]
    PURKINJE -->|"expressed in"| Cortex["Cortex"]
    PURKINJE -->|"expressed in"| Striatum["Striatum"]
    FERROPTOSIS["FERROPTOSIS"] -->|"causes"| PURKINJE
    ATAXIA["ATAXIA"] -->|"sensitizes_to"| PURKINJE
    CEREBELLUM["CEREBELLUM"] -->|"expressed in"| PURKINJE
    PKC["PKC"] -->|"inhibits"| PURKINJE
    VDR["VDR"] -->|"expressed in"| PURKINJE
    ALZHEIMER["ALZHEIMER"] -.protects against.-> PURKINJE
    GCH1["GCH1"] -->|"activates"| PURKINJE
    SCD1["SCD1"] -->|"activates"| PURKINJE

Outgoing (8)

TargetRelationTypeStr
STINGinteracts_withgene0.60

Incoming (79)

SourceRelationTypeStr
ATAXIAsensitizes_todisease0.65
CEREBELLUMexpressed_inbrain_region0.60
NEURONexpressed_incell_type0.60
NEURONSexpressed_incell_type0.60
GABAERGICassociated_withcell_type0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found