VDR

Understanding Entity Pages

This page aggregates everything SciDEX knows about VDR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

VDR is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, inhibits. Associated with Aging, Als, Alzheimer. Connected to 101 entities in the SciDEX knowledge graph.

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graph TD
    VDR["<b>VDR</b>"]
    ferroptosis["ferroptosis"]
    VDR -->|"inhibits"| ferroptosis
    AUTOPHAGY(["AUTOPHAGY"])
    VDR -->|"regulates"| AUTOPHAGY
    Aging{"Aging"}
    VDR -->|"regulates"| Aging
    Alzheimer{"Alzheimer"}
    VDR -->|"regulates"| Alzheimer
    Diabetes{"Diabetes"}
    VDR -->|"inhibits"| Diabetes
    Inflammation{"Inflammation"}
    VDR -->|"inhibits"| Inflammation
    Fibrosis{"Fibrosis"}
    VDR -->|"inhibits"| Fibrosis
    VDR -->|"activates"| Aging
    VDR -->|"activates"| Alzheimer
    Ms{"Ms"}
    VDR -->|"activates"| Ms
    NFE2L2["NFE2L2"]
    VDR -->|"activates"| NFE2L2
    diabetic_nephropathy{"diabetic_nephropathy"}
    VDR -->|"treats"| diabetic_nephropathy
    paricalcitol["paricalcitol"]
    paricalcitol -->|"activates"| VDR
    VITAMIN_D["VITAMIN_D"]
    VITAMIN_D -->|"activates"| VDR
    LOX["LOX"]
    LOX -->|"regulates"| VDR
    SLC7A11["SLC7A11"]
    SLC7A11 -->|"inhibits"| VDR
    NRF2["NRF2"]
    NRF2 -->|"activates"| VDR
    MICRORNAS["MICRORNAS"]
    MICRORNAS -->|"regulates"| VDR
    MIRNAS["MIRNAS"]
    MIRNAS -->|"regulates"| VDR
    GPX4["GPX4"]
    GPX4 -->|"inhibits"| VDR
    AMPK["AMPK"]
    AMPK -->|"activates"| VDR
    ALOX15["ALOX15"]
    ALOX15 -->|"activates"| VDR
    MICRORNAS -->|"activates"| VDR
    MIRNAS -->|"activates"| VDR
    style VDR fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0