TIMM50

Understanding Entity Pages

This page aggregates everything SciDEX knows about TIMM50: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TIMM50 is a gene implicated in neurodegeneration research. Key relationships include: inhibits, regulates, implicated in. Associated with Heart Failure, Ms. Connected to 44 entities in the SciDEX knowledge graph.

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graph TD
    TIMM50["<b>TIMM50</b>"]
    Heart_Failure{"Heart Failure"}
    TIMM50 -->|"regulates"| Heart_Failure
    Ms{"Ms"}
    TIMM50 -->|"inhibits"| Ms
    HSPA9["HSPA9"]
    TIMM50 -->|"inhibits"| HSPA9
    TIMM22["TIMM22"]
    TIMM50 -->|"inhibits"| TIMM22
    MITOPHAGY["MITOPHAGY"]
    TIMM50 -->|"inhibits"| MITOPHAGY
    HSPE1["HSPE1"]
    TIMM50 -->|"inhibits"| HSPE1
    OPA1["OPA1"]
    TIMM50 -->|"regulates"| OPA1
    LAMP2["LAMP2"]
    TIMM50 -->|"inhibits"| LAMP2
    BNIP3L["BNIP3L"]
    TIMM50 -->|"inhibits"| BNIP3L
    MITOCHONDRIAL_DYSFUNCTION["MITOCHONDRIAL DYSFUNCTION"]
    TIMM50 -->|"inhibits"| MITOCHONDRIAL_DYSFUNCTION
    SIRT1["SIRT1"]
    TIMM50 -->|"inhibits"| SIRT1
    HTRA2["HTRA2"]
    TIMM50 -->|"inhibits"| HTRA2
    BNIP3["BNIP3"]
    BNIP3 -->|"inhibits"| TIMM50
    VDAC1["VDAC1"]
    VDAC1 -->|"inhibits"| TIMM50
    FUNDC1["FUNDC1"]
    FUNDC1 -->|"inhibits"| TIMM50
    TOMM20["TOMM20"]
    TOMM20 -->|"inhibits"| TIMM50
    TIMM9["TIMM9"]
    TIMM9 -->|"inhibits"| TIMM50
    TIMM17B["TIMM17B"]
    TIMM17B -->|"inhibits"| TIMM50
    OMA1["OMA1"]
    OMA1 -->|"inhibits"| TIMM50
    TIMM23["TIMM23"]
    TIMM23 -->|"inhibits"| TIMM50
    MTOR["MTOR"]
    MTOR -->|"inhibits"| TIMM50
    NRF1["NRF1"]
    NRF1 -->|"inhibits"| TIMM50
    HSPD1["HSPD1"]
    HSPD1 -->|"regulates"| TIMM50
    MFN2["MFN2"]
    MFN2 -->|"inhibits"| TIMM50
    style TIMM50 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0