gene

TIMM9

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TIMM9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

43Connections
0Hypotheses
0Analyses
39Outgoing
4Incoming

Summary

Translocase of Inner Mitochondrial Membrane 9 - chaperone protein essential for mitochondrial protein import

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🧬 Gene Info
Gene SymbolTIMM9
AliasesTranslocase of Inner Mitochondrial Membrane 9
Protein TypeChaperone
Functionis a small chaperone protein localized in the mitochondrial intermembrane space.
Subcellular Localizationthe mitochondrial intermembrane space. It plays an essential role in the import and insertion of proteins into the inner
Molecular Weight10 kDa
Amino Acids88 aa
PathwaysUnfolded Protein Response, Mitophagy, Mtor
GeneCardsTIMM9
Human Protein AtlasTIMM9
TIMM10Chaperone complex subunit
TIMM22TIM22 translocase core component
TIMM8A/BSmall Tim family members
TOMM40Outer membrane translocase component
Mitochondrial carrier proteinsSubstrate precursors
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsTIMM17B, OMA1, TIMM23, MTOR, NRF1, HSPD1
KG Connections43 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (8)

Knowledge base pages for this entity

Canonical Page

TIMM9

gene · 1695 words

timm17a

gene · 2702 words

TIMM13 Gene

gene · 2289 words

TIMM8A Gene

gene · 2039 words

TIMM17B — Translocase of Inner Mitochondrial Membrane 17B

gene · 1615 words

TIMM10B (Translocase of Inner Mitochondrial Membrane 10 Homolog B)

gene · 1536 words

Pathway Diagram

graph TD
    TIMM9["<b>TIMM9</b>"]
    Heart_Failure{"Heart Failure"}
    TIMM9 -->|"inhibits"| Heart_Failure
    Ms{"Ms"}
    TIMM9 -->|"inhibits"| Ms
    TIMM17B["TIMM17B"]
    TIMM9 -->|"inhibits"| TIMM17B
    OMA1["OMA1"]
    TIMM9 -->|"inhibits"| OMA1
    TIMM23["TIMM23"]
    TIMM9 -->|"inhibits"| TIMM23
    MTOR["MTOR"]
    TIMM9 -->|"inhibits"| MTOR
    NRF1["NRF1"]
    TIMM9 -->|"inhibits"| NRF1
    HSPD1["HSPD1"]
    TIMM9 -->|"inhibits"| HSPD1
    MFN2["MFN2"]
    TIMM9 -->|"inhibits"| MFN2
    MFF["MFF"]
    TIMM9 -->|"inhibits"| MFF
    BECN1["BECN1"]
    TIMM9 -->|"inhibits"| BECN1
    LONP1["LONP1"]
    TIMM9 -->|"inhibits"| LONP1
    BNIP3["BNIP3"]
    BNIP3 -->|"inhibits"| TIMM9
    VDAC1["VDAC1"]
    VDAC1 -->|"inhibits"| TIMM9
    FUNDC1["FUNDC1"]
    FUNDC1 -->|"inhibits"| TIMM9
    TOMM20["TOMM20"]
    TOMM20 -->|"inhibits"| TIMM9
    style TIMM9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (39)

TargetRelationTypeStr
Heart Failureinhibitsdisease0.65
Msinhibitsdisease0.65
TIMM17Binhibitsgene0.60
OMA1inhibitsgene0.60
TIMM23inhibitsgene0.60

Incoming (4)

SourceRelationTypeStr
BNIP3inhibitsgene0.60
VDAC1inhibitsgene0.60
FUNDC1inhibitsgene0.60
TOMM20inhibitsgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found