TNFAIP3

Understanding Entity Pages

This page aggregates everything SciDEX knows about TNFAIP3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TNFAIP3 is a gene implicated in neurodegeneration research. Key relationships include: inhibits, associated with, regulates. Associated with Als, Inflammation, Ischemia. Connected to 38 entities in the SciDEX knowledge graph.

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graph TD
    TNFAIP3["<b>TNFAIP3</b>"]
    Als{"Als"}
    TNFAIP3 -->|"biomarker for"| Als
    Ms{"Ms"}
    TNFAIP3 -->|"biomarker for"| Ms
    Ischemia{"Ischemia"}
    TNFAIP3 -->|"biomarker for"| Ischemia
    TNFAIP3 -->|"associated with"| Als
    TNFAIP3 -->|"associated with"| Ms
    Inflammation{"Inflammation"}
    TNFAIP3 -->|"regulates"| Inflammation
    TNFAIP3 -->|"regulates"| Ischemia
    CEBPB["CEBPB"]
    TNFAIP3 -->|"associated with"| CEBPB
    IRF1["IRF1"]
    TNFAIP3 -->|"associated with"| IRF1
    Nf__b(["Nf-Kappab"])
    TNFAIP3 -->|"biomarker for"| Nf__b
    RIPK3["RIPK3"]
    TNFAIP3 -->|"regulates"| RIPK3
    Necroptosis(["Necroptosis"])
    TNFAIP3 -->|"associated with"| Necroptosis
    HSPA1B["HSPA1B"]
    HSPA1B -->|"associated with"| TNFAIP3
    SERPINE1["SERPINE1"]
    SERPINE1 -->|"associated with"| TNFAIP3
    NF__B["NF-KappaB"]
    NF__B -->|"biomarker for"| TNFAIP3
    HSPA1A["HSPA1A"]
    HSPA1A -->|"associated with"| TNFAIP3
    PYROPTOSIS["PYROPTOSIS"]
    PYROPTOSIS -->|"associated with"| TNFAIP3
    TMEM173["TMEM173"]
    TMEM173 -->|"regulates"| TNFAIP3
    STING1["STING1"]
    STING1 -->|"regulates"| TNFAIP3
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"regulates"| TNFAIP3
    IMMUNE_INFILTRATION["IMMUNE INFILTRATION"]
    IMMUNE_INFILTRATION -->|"associated with"| TNFAIP3
    style TNFAIP3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0