CKB

Understanding Entity Pages

This page aggregates everything SciDEX knows about CKB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CKB is a gene implicated in neurodegeneration research. Key relationships include: inhibits, interacts with, associated with. Associated with ALS, Als, Cardiac. Connected to 37 entities in the SciDEX knowledge graph.

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graph TD
    CKB["<b>CKB</b>"]
    AKT["AKT"]
    CKB -->|"inhibits"| AKT
    HNRNPK["HNRNPK"]
    CKB -->|"interacts with"| HNRNPK
    HSPD1["HSPD1"]
    CKB -->|"interacts with"| HSPD1
    PRDX6["PRDX6"]
    CKB -->|"interacts with"| PRDX6
    TPI1["TPI1"]
    CKB -->|"interacts with"| TPI1
    VCL["VCL"]
    CKB -->|"interacts with"| VCL
    LAMP2["LAMP2"]
    CKB -->|"interacts with"| LAMP2
    FLOT2["FLOT2"]
    CKB -->|"interacts with"| FLOT2
    Bcl2["Bcl2"]
    CKB -->|"interacts with"| Bcl2
    IP3R["IP3R"]
    CKB -->|"interacts with"| IP3R
    Als{"Als"}
    CKB -->|"associated with"| Als
    Cardiac{"Cardiac"}
    CKB -->|"inhibits"| Cardiac
    miR_551a["miR-551a"]
    miR_551a -->|"inhibits"| CKB
    miR_483["miR-483"]
    miR_483 -->|"inhibits"| CKB
    Ribc2["Ribc2"]
    Ribc2 -->|"interacts with"| CKB
    Ybx2["Ybx2"]
    Ybx2 -->|"interacts with"| CKB
    Bmal1["Bmal1"]
    Bmal1 -->|"regulates"| CKB
    BCL2["BCL2"]
    BCL2 -->|"inhibits"| CKB
    ARNT["ARNT"]
    ARNT -->|"inhibits"| CKB
    ARNT -->|"activates"| CKB
    BCL2 -->|"activates"| CKB
    BMAL1["BMAL1"]
    BMAL1 -->|"inhibits"| CKB
    CIRCADIAN_RHYTHM["CIRCADIAN RHYTHM"]
    CIRCADIAN_RHYTHM -->|"inhibits"| CKB
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"inhibits"| CKB
    style CKB fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0