concept

HGF

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HGF: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

68Connections

0Hypotheses

0Analyses

50Outgoing

17Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	HGF
Key Genes/Proteins	SDC1, SUST, JUN
Related Diseases	ALS, Tumor, Cancer, Als, Infection

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    HGF["HGF"]
    HGF -->|"interacts"| MET["MET"]
    HGF -->|"inhibits"| ALS["ALS"]
    HGF -->|"regulates"| Tumor["Tumor"]
    HGF -->|"regulates"| Cancer["Cancer"]
    HGF -->|"target for"| Als["Als"]
    HGF -->|"activates"| Infection["Infection"]
    HGF -->|"activates"| Carcinoma["Carcinoma"]
    SDC1["SDC1"] -->|"interacts"| HGF
    FERROPTOSIS["FERROPTOSIS"] -->|"inhibits"| HGF
    PI3K["PI3K"] -->|"activates"| HGF
    AND["AND"] -->|"regulates"| HGF
    SRC["SRC"] -->|"activates"| HGF
    MET -->|"regulates"| HGF
    WNT["WNT"] -->|"activates"| HGF
    MAPK["MAPK"] -->|"activates"| HGF

Outgoing (51)

Target	Relation	Type	Str
ALS	inhibits	disease	0.65
Tumor	regulates	disease	0.65
Cancer	regulates	disease	0.65
Als	therapeutic_target	disease	0.65
Infection	activates	disease	0.65
Carcinoma	activates	disease	0.65
Ms	associated_with	disease	0.65
Als	inhibits	disease	0.65
Cancer	inhibits	disease	0.65
Als	associated_with	disease	0.65
Aging	therapeutic_target	disease	0.65
Cancer	associated_with	disease	0.65
JUN	inhibits	gene	0.60
Ferroptosis	inhibits	pathway	0.60
AKT	activates	gene	0.60
EGFR	activates	gene	0.60
Wnt	activates	pathway	0.60
Mapk	activates	pathway	0.60
Angiogenesis	activates	pathway	0.60
Akt	activates	pathway	0.60
Pi3K	activates	pathway	0.60
FERROPTOSIS	inhibits	gene	0.60
AND	inhibits	gene	0.60
CCL2	expressed_in	gene	0.60
VEGFA	expressed_in	gene	0.60
CDH1	expressed_in	gene	0.60
ANG	expressed_in	gene	0.60
PLG	expressed_in	gene	0.60
PTEN	expressed_in	gene	0.60
EFNB2	expressed_in	gene	0.60
NFKB1	inhibits	gene	0.60
IL30	expressed_in	gene	0.60
ARG1	therapeutic_target	gene	0.60
Epithelial	associated_with	cell_type	0.60
Macrophage	therapeutic_target	cell_type	0.60
Nk Cell	therapeutic_target	cell_type	0.60
Fibroblast	activates	cell_type	0.60
T Cell	therapeutic_target	cell_type	0.60
Neutrophil	therapeutic_target	cell_type	0.60
ferroptosis	participates_in	pathway	0.60
endothelial cells	expressed_in	cell_type	0.60
ferroptosis	associated_with	process	0.60
ferroptosis	inhibits	process	0.60
VEGF	interacts_with	gene	0.60
VEGF	associated_with	gene	0.60
RNA	inhibits	gene	0.60
oxidative stress response	participates_in	pathway	0.60
MET	regulates	gene	0.60
Alzheimer's disease	regulates	disease	0.60
neurodegeneration	regulates	disease	0.60

Incoming (17)

Source	Relation	Type	Str
SDC1	interacts_with	gene	0.90
SUST	associated_with	gene	0.70
FERROPTOSIS	inhibits	gene	0.60
PI3K	activates	gene	0.60
AND	regulates	gene	0.60
SRC	activates	gene	0.60
MET	regulates	gene	0.60
WNT	activates	gene	0.60
MAPK	activates	gene	0.60
CANCER	regulates	gene	0.60
JUN	inhibits	gene	0.60
AND	inhibits	gene	0.60
EGF	expressed_in	gene	0.60
PD-L1	therapeutic_target	gene	0.60
GLS	therapeutic_target	gene	0.60
EGF	interacts_with	gene	0.60
ALS	regulates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

HGF

Understanding Entity Pages

Wiki Pages (20)

Alzheimer's Disease

Clinical Trials Dashboard

Alzheimer's Drug Discovery Foundation (ADDF)

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Liver-Brain Neurodegeneration Axis

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PLAU Gene (Urokinase)

Fosramatine

Israeli Biotechnology Companies

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