Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about HEMOGLOBIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | HEMOGLOBIN |
Knowledge base pages for this entity
graph TD
HEMOGLOBIN["HEMOGLOBIN"]
HEMOGLOBIN -->|"binds"| Iron["Iron"]
HEMOGLOBIN -->|"regulates"| Cancer["Cancer"]
HEMOGLOBIN -->|"activates"| Aging["Aging"]
HEMOGLOBIN -->|"activates"| Ischemia["Ischemia"]
HEMOGLOBIN -->|"activates"| Stroke["Stroke"]
HEMOGLOBIN -->|"activates"| Neuroinflammation["Neuroinflammation"]
HEMOGLOBIN -.protects against.-> Traumatic_Brain_Injury["Traumatic Brain Injury"]
HEMOGLOBIN -.protects against.-> Alzheimer["Alzheimer"]
FERROPORTIN["FERROPORTIN"] -->|"regulates"| HEMOGLOBIN
DMT1["DMT1"] -->|"regulates"| HEMOGLOBIN
TFR1["TFR1"] -->|"regulates"| HEMOGLOBIN
STROKE["STROKE"] -->|"activates"| HEMOGLOBIN
MMP9["MMP9"] -->|"activates"| HEMOGLOBIN
AEP["AEP"] -->|"inhibits"| HEMOGLOBIN
TRKB["TRKB"] -->|"activates"| HEMOGLOBIN
AGING["AGING"] -->|"activates"| HEMOGLOBIN| Target | Relation | Type | Str |
|---|---|---|---|
| Iron | binds | compound | 0.95 |
| Cancer | regulates | disease | 0.60 |
| Aging | activates | disease | 0.60 |
| Ischemia | activates | disease | 0.60 |
| Stroke | activates | disease | 0.60 |
| Neuroinflammation | activates | disease | 0.60 |
| Traumatic Brain Injury | protects_against | disease | 0.60 |
| Alzheimer | protects_against | disease | 0.60 |
| Neurodegeneration | protects_against | disease | 0.60 |
| Stroke | protects_against | disease | 0.60 |
| Parkinson | protects_against | disease | 0.60 |
| Als | protects_against | disease | 0.60 |
| Ischemia | protects_against | disease | 0.60 |
| Neuroinflammation | protects_against | disease | 0.60 |
| Neuroinflammation | inhibits | disease | 0.60 |
| Alzheimer | regulates | disease | 0.60 |
| Als | inhibits | disease | 0.60 |
| Parkinson | therapeutic_target | disease | 0.60 |
| Neuroinflammation | therapeutic_target | disease | 0.60 |
| Alzheimer | therapeutic_target | disease | 0.60 |
| Pyroptosis | inhibits | disease | 0.60 |
| Stroke | inhibits | disease | 0.60 |
| Multiple Sclerosis | expressed_in | disease | 0.60 |
| Als | expressed_in | disease | 0.60 |
| Blood-Brain Barrier | activates | pathway | 0.55 |
| Mitochondrial Function | protects_against | pathway | 0.55 |
| Oxidative Stress | protects_against | pathway | 0.55 |
| Neurogenesis | protects_against | pathway | 0.55 |
| Oxidative Stress | associated_with | pathway | 0.55 |
| Blood-Brain Barrier | associated_with | pathway | 0.55 |
| Nf-Κb | therapeutic_target | pathway | 0.55 |
| Oxidative Stress | therapeutic_target | pathway | 0.55 |
| Epigenetic | therapeutic_target | pathway | 0.55 |
| Inflammasome | inhibits | pathway | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Iron Metabolism | associated_with | process | 0.88 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||