disease

Pneumonia

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Pneumonia: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

150Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

Disease Info

Associated Genes	IL6, IL6R, INFLAMMATION, STROKE, AND, IL-6
KG Connections	149 knowledge graph edges
Databases	OMIM Orphanet ClinicalTrials PubMed

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Pneumonia["Pneumonia"] -->|"therapeutic target"| Infection["Infection"]
    Pneumonia["Pneumonia"] -->|"therapeutic target"| Mtor["Mtor"]
    Pneumonia["Pneumonia"] -->|"activates"| Apoptosis["Apoptosis"]
    Pneumonia["Pneumonia"] -->|"activates"| Ferroptosis["Ferroptosis"]
    Pneumonia["Pneumonia"] -->|"activates"| Immune_Response["Immune Response"]
    Pneumonia["Pneumonia"] -->|"therapeutic target"| Als["Als"]
    MTOR["MTOR"] -->|"therapeutic target"| Pneumonia["Pneumonia"]
    INFLAMMATION["INFLAMMATION"] -->|"activates"| Pneumonia["Pneumonia"]
    APOPTOSIS["APOPTOSIS"] -->|"activates"| Pneumonia["Pneumonia"]
    GPX4["GPX4"] -->|"regulates"| Pneumonia["Pneumonia"]
    style Pneumonia fill:#ef5350,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (65)

Target	Relation	Type	Str
Infection	therapeutic_target	disease	0.75
Mtor	therapeutic_target	pathway	0.70
Apoptosis	activates	pathway	0.70
Ferroptosis	activates	pathway	0.65
Immune Response	activates	pathway	0.65
Als	therapeutic_target	disease	0.65
Inflammation	activates	disease	0.65
Glycolysis	therapeutic_target	pathway	0.60
Epigenetic	therapeutic_target	pathway	0.60
Immune Response	therapeutic_target	pathway	0.60
Toll-Like Receptor	inhibits	pathway	0.60
Mapk	inhibits	pathway	0.60
Jak-Stat	inhibits	pathway	0.60
Ppar Signaling	inhibits	pathway	0.60
Nf-Κb	regulates	pathway	0.60
Nf-Kb	activates	pathway	0.60
Immune Response	regulates	pathway	0.60
Immune Response	contributes_to	pathway	0.60
Glycolysis	inhibits	pathway	0.60
Pi3K/Akt	activates	pathway	0.60
Phagocytosis	activates	pathway	0.60
Mapk	activates	pathway	0.60
Drug Resistance	therapeutic_target	pathway	0.60
Apoptosis	therapeutic_target	pathway	0.60
Differentiation	biomarker_for	pathway	0.60
Toll-Like Receptor	activates	pathway	0.60
Pi3K/Akt	therapeutic_target	pathway	0.60
Autophagy	regulates	pathway	0.55
Oxidative Stress	activates	pathway	0.55
Sepsis	expressed_in	disease	0.55
Infection	treats	disease	0.55
Als	inhibits	disease	0.55
Hepatitis	treats	disease	0.55
Inflammation	inhibits	disease	0.55
Als	regulates	disease	0.55
Fibrosis	contributes_to	disease	0.55
Cancer	contributes_to	disease	0.55
Copd	contributes_to	disease	0.55
Als	contributes_to	disease	0.55
Asthma	contributes_to	disease	0.55
Pulmonary Fibrosis	contributes_to	disease	0.55
Lung Cancer	contributes_to	disease	0.55
Inflammation	contributes_to	disease	0.55
Infection	activates	disease	0.55
Als	activates	disease	0.55
Inflammation	causes	disease	0.55
Dementia	expressed_in	disease	0.55
Inflammation	biomarker_for	disease	0.55
Sepsis	biomarker_for	disease	0.55
Inflammation	therapeutic_target	disease	0.55

Incoming (85)

Source	Relation	Type	Str
Ischaemic Stroke	causes	disease	0.95
MTOR	therapeutic_target	gene	0.75
INFLAMMATION	activates	gene	0.75
APOPTOSIS	activates	gene	0.75
GPX4	regulates	gene	0.65
NCOA4	activates	gene	0.65
SLC7A11	regulates	gene	0.65
CXCL10	activates	gene	0.65
TNF	activates	gene	0.65
IL6	associated_with	gene	0.65
IL6R	associated_with	gene	0.65
GENES	therapeutic_target	gene	0.65
PPAR	inhibits	gene	0.65
TNF	inhibits	gene	0.65
CYTOKINES	inhibits	gene	0.65
IL-6	inhibits	gene	0.65
INFLAMMATION	inhibits	gene	0.65
TNF-Α	inhibits	gene	0.65
NRF2	inhibits	gene	0.65
AKT	inhibits	gene	0.65
JAK	inhibits	gene	0.65
TSLP	regulates	gene	0.65
FOS	regulates	gene	0.65
TLR4	activates	gene	0.65
AKT	regulates	gene	0.65
PI3K	regulates	gene	0.65
NF-KB	activates	gene	0.65
NF-ΚB	regulates	gene	0.65
EPO	regulates	gene	0.65
AHR	regulates	gene	0.65
MYD88	regulates	gene	0.65
IFN	regulates	gene	0.65
INFLAMMATION	contributes_to	gene	0.65
CANCER	contributes_to	gene	0.65
NAD	inhibits	gene	0.65
ERK	activates	gene	0.65
PI3K	activates	gene	0.65
FERROPTOSIS	activates	gene	0.65
INFLAMMATION	causes	gene	0.65
CCL2	activates	gene	0.65
PHAGOCYTOSIS	activates	gene	0.65
AKT	activates	gene	0.65
ASTROCYTES	expressed_in	gene	0.65
DEMENTIA	expressed_in	gene	0.65
INFLAMMATION	biomarker_for	gene	0.65
INFLAMMATION	therapeutic_target	gene	0.65
DIABETES MELLITUS	therapeutic_target	gene	0.65
APOPTOSIS	therapeutic_target	gene	0.65
CANCER	therapeutic_target	gene	0.65
STROKE	causes	gene	0.65

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Pneumonia

Understanding Entity Pages

Wiki Pages (20)

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