MTORC1

Understanding Entity Pages

This page aggregates everything SciDEX knows about MTORC1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

MTORC1 is a concept in neurodegeneration research. Key relationships include: activates, interacts with, regulates. Associated with AD, ADH, ALS. Connected to 1023 entities in the SciDEX knowledge graph.

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graph TD
    MTORC1["MTORC1"]
    MTORC1 -->|"inhibits"| ULK1["ULK1"]
    MTORC1 -->|"contributes to"| protein_synthesis["protein synthesis"]
    MTORC1 -->|"inhibits"| autophagy["autophagy"]
    MTORC1 -->|"inhibits"| TFEB["TFEB"]
    MTORC1 -->|"inhibits"| AUTOPHAGY["AUTOPHAGY"]
    MTORC1 -->|"activates"| lipogenesis["lipogenesis"]
    PRKAA["PRKAA"] -->|"inhibits"| MTORC1
    endocytosis["endocytosis"] -->|"activates"| MTORC1
    alpha_synuclein["alpha-synuclein"] -->|"activates"| MTORC1
    AKT["AKT"] -->|"activates"| MTORC1
    RAPAMYCIN["RAPAMYCIN"] -->|"inhibits"| MTORC1
    raptor["raptor"] -->|"activates"| MTORC1
    TSC2["TSC2"] -->|"inhibits"| MTORC1
    STING1["STING1"] -->|"activates"| MTORC1