concept

DSDNA

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DSDNA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

230Connections

0Hypotheses

0Analyses

50Outgoing

40Incoming

0Experiments

0Debates

Summary

DSDNA is a concept in neurodegeneration research. Key relationships include: activates, therapeutic target, inhibits. Associated with Als, Alzheimer, Autoimmune. Connected to 168 entities in the SciDEX knowledge graph.

View on Wiki →

No AI portrait yet

Pathway Diagram

graph TD
    DSDNA["DSDNA"]
    DSDNA -->|"activates"| cGAS["cGAS"]
    DSDNA -->|"activates"| Cancer["Cancer"]
    DSDNA -->|"activates"| Als["Als"]
    DSDNA -->|"activates"| Tumor["Tumor"]
    DSDNA -->|"activates"| Ms["Ms"]
    DSDNA -->|"activates"| Ischemia["Ischemia"]
    DSDNA -->|"activates"| Cardiac["Cardiac"]
    DSDNA -->|"activates"| Inflammation["Inflammation"]
    DSDNA -->|"activates"| Neuroinflammation["Neuroinflammation"]
    DSDNA -->|"target for"| Senescence["Senescence"]
    IKBKB["IKBKB"] -->|"target for"| DSDNA
    CXCL10["CXCL10"] -->|"activates"| DSDNA
    GENES["GENES"] -->|"activates"| DSDNA
    MTOR["MTOR"] -->|"phosphorylates"| DSDNA

Outgoing (190)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:DSDNA	data_in	dataset_row	0.00
cGAS	activates	protein	1.00
CGAS-STING	activates	gene	1.00
DNA	activates	gene	1.00
STING	activates	gene	1.00
GENES	activates	gene	0.90
Als	activates	disease	0.85
Cancer	activates	disease	0.85
Tumor	activates	disease	0.75
IRF3	activates	gene	0.70
Pyroptosis	activates	pathway	0.70
PYROPTOSIS	activates	gene	0.70
IFN	activates	gene	0.70
CGAS	inhibits	gene	0.70
STING	inhibits	gene	0.70
UBIQUITIN	inhibits	gene	0.70
NEURODEGENERATIVE DISEASES	therapeutic_target	gene	0.70
Als	implicated_in	disease	0.65
Inflammation	implicated_in	disease	0.65
Ischemia	activates	disease	0.65
Carcinoma	activates	disease	0.65
Hepatocellular Carcinoma	activates	disease	0.65
Infection	regulates	disease	0.65
Inflammation	regulates	disease	0.65
Cardiac	activates	disease	0.65
Inflammation	activates	disease	0.65
Fibrosis	activates	disease	0.65
Neuroinflammation	activates	disease	0.65
Ms	activates	disease	0.65
Als	inhibits	disease	0.65
Tumor	inhibits	disease	0.65
Senescence	therapeutic_target	disease	0.65
Ms	therapeutic_target	disease	0.65
Autoimmune	therapeutic_target	disease	0.65
Autoimmune	associated_with	disease	0.65
Tumor	implicated_in	disease	0.65
Infection	implicated_in	disease	0.65
Infection	associated_with	disease	0.65
Aging	expressed_in	disease	0.65
Sepsis	activates	disease	0.65
Pneumonia	activates	disease	0.65
Glaucoma	activates	disease	0.65
Tauopathy	activates	disease	0.65
Neuroinflammation	therapeutic_target	disease	0.65
Senescence	activates	disease	0.65
Alzheimer	activates	disease	0.65
Inflammation	therapeutic_target	disease	0.65
Neurodegeneration	activates	disease	0.65
Copd	therapeutic_target	disease	0.65
Inflammation	protects_against	disease	0.65

Incoming (40)

Source	Relation	Type	Str
benchmark_ot_ad_answer_key:DSDNA	data_in	dataset_row	0.00
GENES	activates	gene	0.60
TNFAIP3	inhibits	gene	0.60
IKBKB	phosphorylates	gene	0.60
GAIN	phosphorylates	gene	0.60
CXCL10	activates	gene	0.60
AND	phosphorylates	gene	0.60
HIPPO	phosphorylates	gene	0.60
NEK7	inhibits	gene	0.60
NLRP3	inhibits	gene	0.60
TBK1	activates	gene	0.60
INFLAMMATION	protects_against	gene	0.60
DNA	therapeutic_target	gene	0.60
NEURODEGENERATION	activates	gene	0.60
TAU	activates	gene	0.60
IFNAR1	activates	gene	0.60
DNA	activates	gene	0.60
CHUK	associated_with	gene	0.60
INFLAMMATION	regulates	gene	0.60
GENES	regulates	gene	0.60
DNA	associated_with	gene	0.60
OXIDATIVE STRESS	activates	gene	0.60
IKBKB	therapeutic_target	gene	0.60
TBK1	interacts_with	gene	0.60
CGAS	associated_with	gene	0.60
VIRAL INFECTIONS	activates	gene	0.60
GAIN	therapeutic_target	gene	0.60
MTOR	therapeutic_target	gene	0.60
MTOR	phosphorylates	gene	0.60
GPX4	activates	gene	0.60
INFLAMMATION	activates	gene	0.60
CGAS	activates	gene	0.60
CGAS	inhibits	gene	0.60
HEXB	inhibits	gene	0.60
GBA	inhibits	gene	0.60
AUTOPHAGY	activates	gene	0.60
AND	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
STING	activates	gene	0.50
ferroptosis	activates	phenotype	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity