OGT

Understanding Entity Pages

This page aggregates everything SciDEX knows about OGT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Gene profile: OGT - O-GlcNAc N-acetylglucosaminyltransferase, the enzyme that adds O-GlcNAc to proteins, central to O-GlcNAcylation cycling

View on Wiki →

graph TD
    OGT["<b>OGT</b>"]
    Carcinoma{"Carcinoma"}
    OGT -->|"contributes to"| Carcinoma
    Ms{"Ms"}
    OGT -->|"activates"| Ms
    Tumor{"Tumor"}
    OGT -->|"contributes to"| Tumor
    OGT -->|"activates"| Carcinoma
    Cancer{"Cancer"}
    OGT -->|"activates"| Cancer
    Als{"Als"}
    OGT -->|"activates"| Als
    OGT -->|"regulates"| Als
    Inflammation{"Inflammation"}
    OGT -->|"activates"| Inflammation
    OGT -->|"regulates"| Ms
    Depression{"Depression"}
    OGT -->|"activates"| Depression
    FOXK2["FOXK2"]
    OGT -->|"regulates"| FOXK2
    HCC{"HCC"}
    OGT -->|"contributes to"| HCC
    ROS["ROS"]
    ROS -->|"activates"| OGT
    SLC7A11["SLC7A11"]
    SLC7A11 -->|"activates"| OGT
    STX17["STX17"]
    STX17 -->|"activates"| OGT
    FOXK2 -->|"activates"| OGT
    ULK1["ULK1"]
    ULK1 -->|"activates"| OGT
    FERROPTOSIS["FERROPTOSIS"]
    FERROPTOSIS -->|"associated with"| OGT
    ENO1["ENO1"]
    ENO1 -->|"regulates"| OGT
    TLR["TLR"]
    TLR -->|"regulates"| OGT
    EXOSOMES["EXOSOMES"]
    EXOSOMES -->|"regulates"| OGT
    TRAF6["TRAF6"]
    TRAF6 -->|"regulates"| OGT
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"regulates"| OGT
    ASTROCYTE["ASTROCYTE"]
    ASTROCYTE -->|"regulates"| OGT
    style OGT fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0