SGK1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SGK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SGK1 is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, therapeutic target. Associated with Als, Cardiac, Depression. Connected to 37 entities in the SciDEX knowledge graph.

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graph TD
    SGK1["<b>SGK1</b>"]
    Als{"Als"}
    SGK1 -->|"associated with"| Als
    Ms{"Ms"}
    SGK1 -->|"associated with"| Ms
    Depression{"Depression"}
    SGK1 -->|"associated with"| Depression
    Inflammation{"Inflammation"}
    SGK1 -->|"associated with"| Inflammation
    Lymphoma{"Lymphoma"}
    SGK1 -->|"associated with"| Lymphoma
    SGK1 -->|"therapeutic target"| Ms
    Tumor{"Tumor"}
    SGK1 -->|"therapeutic target"| Tumor
    FKBP5["FKBP5"]
    SGK1 -->|"associated with"| FKBP5
    A2M["A2M"]
    SGK1 -->|"associated with"| A2M
    AQP4["AQP4"]
    SGK1 -->|"associated with"| AQP4
    TNF["TNF"]
    SGK1 -->|"associated with"| TNF
    P2RX7["P2RX7"]
    SGK1 -->|"associated with"| P2RX7
    BCL2["BCL2"]
    BCL2 -->|"associated with"| SGK1
    TP53["TP53"]
    TP53 -->|"therapeutic target"| SGK1
    TET2["TET2"]
    TET2 -->|"associated with"| SGK1
    style SGK1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0