CS

Understanding Entity Pages

This page aggregates everything SciDEX knows about CS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CS encodes citrate synthase, a key mitochondrial enzyme in the TCA cycle with important roles in neuronal energy metabolism and neurodegeneration.

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flowchart TD
    N0["CS"]
    N1["neurodegeneration"]
    N0 -->|"associated with"| N1
    N2["PINK1"]
    N0 -->|"activates"| N2
    N3["PRKN"]
    N0 -->|"activates"| N3
    N4["senescence"]
    N0 -->|"participates in"| N4
    N5["CXCL1"]
    N0 -->|"activates"| N5
    N6["CXCL8"]
    N0 -->|"activates"| N6
    N7["GLB1"]
    N0 -->|"activates"| N7
    N8["LC3"]
    N0 -->|"activates"| N8

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    class N8 gene