concept

CYP19A1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYP19A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

161Connections
0Hypotheses
0Analyses
50Outgoing
50Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameCYP19A1
Key Genes/ProteinsTFEB, RNA, LC3B, UVRAG, AMBRA1, BECN1
Related Diseasessex differences, Cardiovascular, Cancer, Neurodegeneration, Parkinson

Wiki Pages (2)

Knowledge base pages for this entity

CYP11A1 Gene - Cholesterol Side-Chain Cleavage Enzyme

gene · 2028 words

Autism Spectrum Disorder

disease · 1078 words

Pathway Diagram

graph TD
    CYP19A1["CYP19A1"]
    CYP19A1 -->|"involved_in"| Estradiol["Estradiol"]
    CYP19A1 -->|"regulates"| Sex_Differences_In_Autophagy["Sex Differences In Autophagy"]
    CYP19A1 -->|"expressed in"| Inflammation["Inflammation"]
    CYP19A1 -->|"expressed in"| STAR["STAR"]
    CYP19A1 -->|"expressed in"| IL_6["IL-6"]
    CYP19A1 -->|"expressed in"| Nf__b["Nf-Kappab"]
    CYP19A1 -->|"expressed in"| AND["AND"]
    CYP19A1 -->|"expressed in"| SIRT1["SIRT1"]
    TFEB["TFEB"] -->|"binds_to"| CYP19A1
    AMPK["AMPK"] -->|"expressed in"| CYP19A1
    CYP17A1["CYP17A1"] -->|"expressed in"| CYP19A1
    SIRT1 -->|"expressed in"| CYP19A1
    IL_1["IL-1"] -->|"expressed in"| CYP19A1
    STAR -->|"expressed in"| CYP19A1
    INFLAMMATION["INFLAMMATION"] -->|"expressed in"| CYP19A1
    INSULIN_RESISTANCE["INSULIN RESISTANCE"] -->|"expressed in"| CYP19A1

Outgoing (99)

TargetRelationTypeStr
sex differencesdrivesphenotype0.75
Cardiovascularassociated_withdisease0.65
Cancerassociated_withdisease0.65
Neurodegenerationassociated_withdisease0.65
Parkinsonassociated_withdisease0.65

Incoming (62)

SourceRelationTypeStr
TFEBbinds_toprotein0.90
NEURODEGENERATIONassociated_withgene0.60
BCL2L1associated_withgene0.60
LAMP2associated_withgene0.60
PSEN2associated_withgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found