Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LNCRNA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
LNCRNA["LNCRNA"]
style LNCRNA fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
LNCRNA -->|"involved_in"| Cancer_Initiation["Cancer Initiation"]
LNCRNA -->|"involved_in"| Cancer_Development["Cancer Development"]
LNCRNA -->|"regulates"| Chromatin_Organization["Chromatin Organization"]
LNCRNA -->|"regulates"| Transcriptional_Regulation["Transcriptional Regulation"]
LNCRNA -->|"regulates"| Post_transcriptional_Regulatio["Post-transcriptional Regulation"]
LNCRNA -->|"contributes to"| Tumor_Initiation["Tumor Initiation"]
LNCRNA -->|"contributes to"| Tumor_Growth["Tumor Growth"]
LNCRNA -->|"contributes to"| Metastasis["Metastasis"]
INFLAMMATION([INFLAMMATION]) -->|"activates"| LNCRNA
GAP43([GAP43]) -->|"activates"| LNCRNA
RNA([RNA]) -->|"activates"| LNCRNA
AND([AND]) -->|"activates"| LNCRNA
LOC100911717([LOC100911717]) -->|"activates"| LNCRNA
DNA([DNA]) -->|"regulates"| LNCRNA
MIR31HG([MIR31HG]) -->|"activates"| LNCRNA
HUNTINGTON([HUNTINGTON]) -->|"activates"| LNCRNA| Target | Relation | Type | Str |
|---|---|---|---|
| Programmed Cell Death | regulates | process | 0.95 |
| Cancer Initiation | involved_in | process | 0.90 |
| Cancer Development | involved_in | process | 0.90 |
| PARKINSON'S DISEASE | biomarker_for | disease | 0.85 |
| Tumor Initiation | contributes_to | process | 0.85 |
| Tumor Growth | contributes_to | process | 0.85 |
| Chromatin Organization | regulates | process | 0.85 |
| Transcriptional Regulation | regulates | process | 0.85 |
| Post-transcriptional Regulation | regulates | process | 0.85 |
| Neurodegeneration | biomarker_for | process | 0.85 |
| APOPTOSIS | regulates | process | 0.85 |
| AUTOPHAGY | regulates | process | 0.85 |
| ALZHEIMER'S DISEASE | biomarker_for | disease | 0.85 |
| Chromatin Organization | regulates | process | 0.85 |
| Cancer Initiation | involved_in | disease | 0.85 |
| Transcriptional Regulation | regulates | process | 0.85 |
| Metastasis | contributes_to | process | 0.85 |
| Aging | biomarker_for | process | 0.80 |
| Amyotrophic Lateral Sclerosis | modulates | disease | 0.80 |
| Dna | interacts_with | compound | 0.80 |
| Amyotrophic Lateral Sclerosis | therapeutic_target | disease | 0.80 |
| PROTEIN | interacts_with | protein | 0.80 |
| Rna | interacts_with | compound | 0.80 |
| Huntington's Disease | modulates | disease | 0.80 |
| Huntington's Disease | therapeutic_target | disease | 0.80 |
| Alzheimer'S Disease | modulates | disease | 0.80 |
| Cancer Metastasis | involved_in | disease | 0.80 |
| Cancer Diagnosis | biomarker_for | process | 0.75 |
| Cancer Therapy | involved_in | process | 0.70 |
| Pyroptosis | associated_with | disease | 0.65 |
| Ferroptosis | associated_with | disease | 0.65 |
| Necroptosis | associated_with | disease | 0.65 |
| Als | therapeutic_target | disease | 0.65 |
| Neurodegeneration | activates | disease | 0.65 |
| Tumor | expressed_in | disease | 0.65 |
| Tumor | inhibits | disease | 0.65 |
| ALS | inhibits | disease | 0.65 |
| Cancer | activates | disease | 0.65 |
| Senescence | activates | disease | 0.65 |
| Cancer | regulates | disease | 0.65 |
| Tumor | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| Amyotrophic Lateral Sclerosis | activates | disease | 0.65 |
| Parkinson | activates | disease | 0.65 |
| Alzheimer | regulates | disease | 0.65 |
| Alzheimer | activates | disease | 0.65 |
| Pyroptosis | biomarker_for | disease | 0.65 |
| Necroptosis | biomarker_for | disease | 0.65 |
| Ferroptosis | biomarker_for | disease | 0.65 |
| Huntington | activates | disease | 0.65 |
| Source | Relation | Type | Str |
|---|---|---|---|
| INFLAMMATION | activates | gene | 0.60 |
| GAP43 | activates | gene | 0.60 |
| RNA | activates | gene | 0.60 |
| AND | activates | gene | 0.60 |
| LOC100911717 | activates | gene | 0.60 |
| DNA | activates | gene | 0.60 |
| AMYOTROPHIC LATERAL SCLEROSIS | activates | gene | 0.60 |
| PARKINSON | activates | gene | 0.60 |
| ALZHEIMER | activates | gene | 0.60 |
| HUNTINGTIN | activates | gene | 0.60 |
| HUNTINGTON'S DISEASE | activates | gene | 0.60 |
| ALZHEIMER'S DISEASE | activates | gene | 0.60 |
| NEURODEGENERATIVE DISEASES | regulates | gene | 0.60 |
| GBM | interacts_with | gene | 0.60 |
| APOPTOSIS | inhibits | gene | 0.60 |
| RNA | interacts_with | gene | 0.60 |
| MIR-1269 | interacts_with | gene | 0.60 |
| AND | inhibits | gene | 0.60 |
| SLC16A1-AS1 | interacts_with | gene | 0.60 |
| AND | interacts_with | gene | 0.60 |
| ABCA7 | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
| APOE | activates | gene | 0.60 |
| CD2AP | activates | gene | 0.60 |
| EPHA1 | activates | gene | 0.60 |
| CLU | activates | gene | 0.60 |
| BIN1 | activates | gene | 0.60 |
| CASS4 | activates | gene | 0.60 |
| CD33 | activates | gene | 0.60 |
| C-MYC | contributes_to | gene | 0.60 |
| RNA | contributes_to | gene | 0.60 |
| MAPK10 | regulates | gene | 0.60 |
| SLC16A1 | interacts_with | gene | 0.60 |
| P62 | activates | gene | 0.60 |
| FOSL2 | activates | gene | 0.60 |
| GSH | activates | gene | 0.60 |
| NAMPT | activates | gene | 0.60 |
| MYC | associated_with | gene | 0.60 |
| TRAF6 | inhibits | gene | 0.60 |
| C-MYC | associated_with | gene | 0.60 |
| HDAC3 | inhibits | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| MIRNAS | therapeutic_target | gene | 0.60 |
| MICRORNAS | therapeutic_target | gene | 0.60 |
| CDKN2B-AS1 | encodes | gene | 0.60 |
| RNA | therapeutic_target | gene | 0.60 |
| APOPTOSIS | associated_with | gene | 0.60 |
| DNA | regulates | gene | 0.60 |
| RNA | regulates | gene | 0.60 |
| AND | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity