PKM

Understanding Entity Pages

This page aggregates everything SciDEX knows about PKM: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Page for PKM Zeta

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graph TD
    PKM(["PKM"])
    Glycolysis["Glycolysis"]
    Tumor["Tumor"]
    Cancer["Cancer"]
    Als["Als"]
    Neurodegeneration["Neurodegeneration"]
    Neuroinflammation["Neuroinflammation"]
    FASN["FASN"]
    LDHA["LDHA"]
    HK1["HK1"]
    HK2["HK2"]
    HIF["HIF"]
    AKT["AKT"]
    AMPK["AMPK"]
    GLUT1["GLUT1"]
    AND["AND"]
    LDHB["LDHB"]
    CANCER["CANCER"]
    GENES["GENES"]
    SRC["SRC"]
    G6PD["G6PD"]
    PKM -->|"involved in"| Glycolysis
    PKM -->|"activates"| Tumor
    PKM -->|"activates"| Cancer
    PKM -->|"protects_agains"| Als
    PKM -->|"protects_agains"| Neurodegeneration
    PKM -->|"protects_agains"| Neuroinflammation
    PKM -->|"activates"| FASN
    PKM -->|"activates"| LDHA
    PKM -->|"activates"| HK1
    PKM -->|"activates"| HK2
    PKM -->|"activates"| HIF
    PKM -->|"activates"| AKT
    PKM -->|"activates"| AMPK
    PKM -->|"activates"| GLUT1
    PKM -->|"activates"| AND
    PKM -->|"activates"| LDHB
    PKM -->|"activates"| CANCER
    PKM -->|"activates"| GENES
    PKM -->|"activates"| SRC
    PKM -->|"activates"| G6PD
    style PKM fill:#006494,stroke:#333,color:#e0e0e0,stroke-width:2px