Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SPINOCEREBELLAR ATAXIA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SPINOCEREBELLAR ATAXIA |
| Related Diseases | PARKINSON'S DISEASE, AUTOPHAGY, AMYOTROPHIC LATERAL SCLEROSIS, HUNTINGTON'S DISEASE |
| Related Pathways | DNA DAMAGE RESPONSE |
Knowledge base pages for this entity
graph TD
SPINOCEREBELLAR_ATAXIA["SPINOCEREBELLAR ATAXIA"]
TREHALOSE["TREHALOSE"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
NEURODEGENERATION["NEURODEGENERATION"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
ATG10["ATG10"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
ATG12["ATG12"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
CALCINEURIN["CALCINEURIN"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
GENES["GENES"] -->|"activates"| SPINOCEREBELLAR_ATAXIA
NEURODEGENERATIVE_DISORDERS["NEURODEGENERATIVE DISORDERS"] -->|"regulates"| SPINOCEREBELLAR_ATAXIA
PKC["PKC"] -->|"causes"| SPINOCEREBELLAR_ATAXIA
PRKCG["PRKCG"] -->|"causes"| SPINOCEREBELLAR_ATAXIA| Target | Relation | Type | Str |
|---|---|---|---|
| PURKINJE CELLS | causes | cell_type | 0.65 |
| AMYOTROPHIC LATERAL SCLEROSIS | implicated_in | disease | 0.55 |
| DNA DAMAGE RESPONSE | associated_with | pathway | 0.45 |
| RAPAMYCIN | associated_with | drug | 0.45 |
| LEVODOPA | associated_with | drug | 0.45 |
| DEFERIPRONE | associated_with | drug | 0.45 |
| SODIUM BUTYRATE | associated_with | drug | 0.45 |
| Source | Relation | Type | Str |
|---|---|---|---|
| PARKINSON'S DISEASE | interacts_with | disease | 0.65 |
| AUTOPHAGY | causes | phenotype | 0.65 |
| HUNTINGTON'S DISEASE | depleted_in | disease | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||