cell_type

Dendritic Cell

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Dendritic Cell: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

461Connections

0Hypotheses

0Analyses

10Outgoing

50Incoming

Summary

Dendritic Cell is a cell type relevant to neurodegeneration research. Key relationships include: expressed in. Connected to 88 entities in the SciDEX knowledge graph.

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🧫 Cell Type Info

Cell Type	Dendritic Cell
Related Genes	FERROPTOSIS, HER2, PD-L1, CGAS-STING, CD8, RIPK3
Linked Hypotheses	52 hypotheses

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    ROS["ROS"] -->|"expressed in"| Dendritic_Cell["Dendritic Cell"]
    RICTOR["RICTOR"] -->|"expressed in"| Dendritic_Cell["Dendritic Cell"]
    MTOR["MTOR"] -->|"expressed in"| Dendritic_Cell["Dendritic Cell"]
    MAP1LC3A["MAP1LC3A"] -->|"expressed in"| Dendritic_Cell["Dendritic Cell"]
    style Dendritic_Cell fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (62)

Target	Relation	Type	Str
CYP1A1	activates	concept	0.50
DNA DAMAGE	activates	concept	0.50
COLORECTAL CANCER	activates	disease	0.50
Microrna	activates	pathway	0.50
Inflammatory Bowel Disease	activates	disease	0.50
Reactive Oxygen Species	activates	process	0.50
RAPAMYCIN	activates	concept	0.50
NUCLEUS	activates	concept	0.50
ENDOPLASMIC RETICULUM	activates	concept	0.50
PEROXISOME	activates	concept	0.50

Incoming (399)

Source	Relation	Type	Str
PCBMA-TAPP	activates	compound	0.90
Autophagy	modulates	process	0.80
EIF2AK3	interacts_with	gene	0.60
SQSTM1	interacts_with	gene	0.60
HMGB1	interacts_with	gene	0.60
OPTINEURIN	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
WNT	interacts_with	gene	0.60
APC	interacts_with	gene	0.60
ATF6	interacts_with	gene	0.60
RPS6KB1	interacts_with	gene	0.60
GABA	interacts_with	gene	0.60
ATG	interacts_with	gene	0.60
STING1	interacts_with	gene	0.60
AMPK	interacts_with	gene	0.60
MLKL	interacts_with	gene	0.60
RIPK1	interacts_with	gene	0.60
MTOR	interacts_with	gene	0.60
EGF	interacts_with	gene	0.60
RB1	interacts_with	gene	0.60
HSP70	interacts_with	gene	0.60
ATG16L1	interacts_with	gene	0.60
AKT1S1	interacts_with	gene	0.60
RHEB	interacts_with	gene	0.60
ERN1	interacts_with	gene	0.60
GABARAP	interacts_with	gene	0.60
LRRK2	interacts_with	gene	0.60
DEPTOR	interacts_with	gene	0.60
CGAS	interacts_with	gene	0.60
STAT3	interacts_with	gene	0.60
ROS	interacts_with	gene	0.60
AUTOPHAGY	interacts_with	gene	0.60
TFEB	interacts_with	gene	0.60
IFN	interacts_with	gene	0.60
NLR	interacts_with	gene	0.60
MLST8	interacts_with	gene	0.60
PI3K	interacts_with	gene	0.60
BECN1	interacts_with	gene	0.60
CYP1A1	interacts_with	gene	0.60
RAS	interacts_with	gene	0.60
CFTR	interacts_with	gene	0.60
EGFR	interacts_with	gene	0.60
NBR1	interacts_with	gene	0.60
MTORC1	interacts_with	gene	0.60
CASP3	interacts_with	gene	0.60
ATP	interacts_with	gene	0.60
DNA	interacts_with	gene	0.60
OPTN	interacts_with	gene	0.60
NRBF2	interacts_with	gene	0.60
RPTOR	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Dendritic Cell

Understanding Entity Pages

Summary

Wiki Pages (20)

TREM2 Microglial Signaling Pathway in Neurodegeneration

nlrc5-protein

Histamine

Exosome and Extracellular Vesicle Brain Delivery

Gut-Microbiome-Neurodegeneration Axis

Meningeal Lymphatics

IL28B (Interleukin 28B)

MS4A4A Gene — Membrane-Spanning 4-Domains A4A

Adaptive Immunity in Neurodegeneration

CD200R1 Gene

Exosome Biogenesis in Neurodegeneration

NICASTRIN Gene

Subacute Sclerosing Panencephalitis (SSPE)

CTS Gene - Cathepsin S

Safety and Clinical Outcomes Study: Amniotic and Umbilical Cord Tissue Admini... (NCT03899298)

IL3 (Interleukin 3)

Intercellular Adhesion Molecule-5 Protein

CD33 — Cluster of Differentiation 33