YAP1

Understanding Entity Pages

This page aggregates everything SciDEX knows about YAP1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

YAP1 is a gene implicated in neurodegeneration research. Key relationships include: activates, regulates, contributes to. Associated with Als, Cancer, Carcinoma. Connected to 87 entities in the SciDEX knowledge graph.

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flowchart TD
    YAP1["YAP1"] -->|"activates"| LOX["LOX"]
    PTEN["PTEN"] -->|"activates"| YAP1["YAP1"]
    YAP1["YAP1"] -->|"activates"| Tumor["Tumor"]
    YAP1["YAP1"] -->|"activates"| Glioblastoma["Glioblastoma"]
    YAP1["YAP1"] -->|"therapeutic target"| Als["Als"]
    YAP1["YAP1"] -->|"therapeutic target"| Cancer["Cancer"]
    YAP1["YAP1"] -->|"therapeutic target"| Tumor["Tumor"]
    YAP1["YAP1"] -->|"activates"| Diabetes["Diabetes"]
    YAP1["YAP1"] -->|"activates"| Als["Als"]
    YAP1["YAP1"] -->|"contributes to"| Heart_Failure["Heart Failure"]
    YAP1["YAP1"] -->|"contributes to"| Cardiovascular["Cardiovascular"]
    YAP1["YAP1"] -->|"associated with"| Als["Als"]
    style YAP1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style LOX fill:#006494,stroke:#333,color:#e0e0e0
    style PTEN fill:#4a1a6b,stroke:#333,color:#e0e0e0
    style Tumor fill:#ef5350,stroke:#333,color:#e0e0e0
    style Glioblastoma fill:#ef5350,stroke:#333,color:#e0e0e0
    style Als fill:#ef5350,stroke:#333,color:#e0e0e0
    style Cancer fill:#ef5350,stroke:#333,color:#e0e0e0
    style Diabetes fill:#ef5350,stroke:#333,color:#e0e0e0
    style Heart_Failure fill:#ef5350,stroke:#333,color:#e0e0e0
    style Cardiovascular fill:#ef5350,stroke:#333,color:#e0e0e0