concept

CYP1A1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CYP1A1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

338Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

Summary

CYP1A1 is a concept in neurodegeneration research. Key relationships include: interacts with, associated with, expressed in. Associated with ALS, Cancer, Carcinoma. Connected to 110 entities in the SciDEX knowledge graph.

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💡 Concept Info

Name	CYP1A1
Key Genes/Proteins	P38, PI3K, MLST8
Related Diseases	Carcinoma, ALS, Fibrosis, Cancer, Lung Cancer

Wiki Pages (3)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    CYP1A1["CYP1A1"]
    CYP1A1 -->|"expressed in"| Carcinoma["Carcinoma"]
    CYP1A1 -->|"interacts"| ALS["ALS"]
    CYP1A1 -->|"interacts"| Fibrosis["Fibrosis"]
    CYP1A1 -->|"interacts"| Cancer["Cancer"]
    CYP1A1 -->|"interacts"| P38["P38"]
    CYP1A1 -->|"interacts"| PI3K["PI3K"]
    CYP1A1 -->|"interacts"| MLST8["MLST8"]
    CYP1A1 -->|"interacts"| AUTOPHAGY["AUTOPHAGY"]
    CYP1A1 -->|"interacts"| AKT1["AKT1"]
    CYP1A1 -->|"interacts"| IFN["IFN"]
    ROS["ROS"] -->|"interacts"| CYP1A1
    RICTOR["RICTOR"] -->|"interacts"| CYP1A1
    MTOR["MTOR"] -->|"interacts"| CYP1A1
    MAP1LC3A["MAP1LC3A"] -->|"interacts"| CYP1A1
    LC3["LC3"] -->|"interacts"| CYP1A1
    DNA["DNA"] -->|"interacts"| CYP1A1
    RHEB["RHEB"] -->|"interacts"| CYP1A1
    LYSOSOME["LYSOSOME"] -->|"interacts"| CYP1A1
    MAVS["MAVS"] -->|"interacts"| CYP1A1
    RB1["RB1"] -->|"interacts"| CYP1A1

Outgoing (188)

Target	Relation	Type	Str
Carcinoma	expressed_in	disease	0.80
ALS	interacts_with	disease	0.65
Fibrosis	interacts_with	disease	0.65
Cancer	interacts_with	disease	0.65
Cancer	associated_with	disease	0.65
Lung Cancer	associated_with	disease	0.65
Carcinoma	associated_with	disease	0.65
Als	interacts_with	disease	0.65
Diabetes	inhibits	disease	0.65
Fibrosis	inhibits	disease	0.65
Cardiovascular	inhibits	disease	0.65
Cardiomyopathy	inhibits	disease	0.65
P38	interacts_with	gene	0.60
PI3K	interacts_with	gene	0.60
MLST8	interacts_with	gene	0.60
AUTOPHAGY	interacts_with	gene	0.60
AKT1	interacts_with	gene	0.60
IFN	interacts_with	gene	0.60
HMGB1	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
JNK	interacts_with	gene	0.60
PIK3C3	interacts_with	gene	0.60
TFE3	interacts_with	gene	0.60
EGF	interacts_with	gene	0.60
GABARAP	interacts_with	gene	0.60
HSP70	interacts_with	gene	0.60
BECN1	interacts_with	gene	0.60
TFEB	interacts_with	gene	0.60
EIF2AK3	interacts_with	gene	0.60
CDH1	interacts_with	gene	0.60
IFNG	interacts_with	gene	0.60
FIP200	interacts_with	gene	0.60
GENES	interacts_with	gene	0.60
DEPTOR	interacts_with	gene	0.60
RAS	interacts_with	gene	0.60
STING1	interacts_with	gene	0.60
Wnt	interacts_with	pathway	0.60
Autophagy	interacts_with	pathway	0.60
Mapk	interacts_with	pathway	0.60
Mtor	interacts_with	pathway	0.60
Oxidative Phosphorylation	interacts_with	pathway	0.60
RB1	interacts_with	gene	0.60
RHEB	interacts_with	gene	0.60
CASP3	interacts_with	gene	0.60
AKT1S1	interacts_with	gene	0.60
ROS	interacts_with	gene	0.60
ATG16L1	interacts_with	gene	0.60
NBR1	interacts_with	gene	0.60
RPS6KB1	interacts_with	gene	0.60
CYP2D6	associated_with	gene	0.60

Incoming (150)

Source	Relation	Type	Str
ROS	interacts_with	gene	0.60
RICTOR	interacts_with	gene	0.60
MTOR	interacts_with	gene	0.60
MAP1LC3A	interacts_with	gene	0.60
LC3	interacts_with	gene	0.60
DNA	interacts_with	gene	0.60
RHEB	interacts_with	gene	0.60
LYSOSOME	interacts_with	gene	0.60
MAVS	interacts_with	gene	0.60
RB1	interacts_with	gene	0.60
EGFR	interacts_with	gene	0.60
RPTOR	interacts_with	gene	0.60
MTORC1	interacts_with	gene	0.60
LRRK2	interacts_with	gene	0.60
CANCER	interacts_with	gene	0.60
ATG16L1	interacts_with	gene	0.60
ATG	interacts_with	gene	0.60
DDIT3	interacts_with	gene	0.60
SQSTM1	interacts_with	gene	0.60
CFTR	interacts_with	gene	0.60
CGAS	interacts_with	gene	0.60
RB1CC1	interacts_with	gene	0.60
APC	interacts_with	gene	0.60
AMBRA1	interacts_with	gene	0.60
RIPK1	interacts_with	gene	0.60
CASP3	interacts_with	gene	0.60
ERN1	interacts_with	gene	0.60
OPTN	interacts_with	gene	0.60
GRB2	interacts_with	gene	0.60
AMPK	interacts_with	gene	0.60
MAPK14	interacts_with	gene	0.60
MLKL	interacts_with	gene	0.60
CALCOCO2	interacts_with	gene	0.60
NBR1	interacts_with	gene	0.60
EIF2A	interacts_with	gene	0.60
ATF6	interacts_with	gene	0.60
STAT3	interacts_with	gene	0.60
OPTINEURIN	interacts_with	gene	0.60
RPS6KB1	interacts_with	gene	0.60
HSPA5	interacts_with	gene	0.60
ATP	interacts_with	gene	0.60
DEPTOR	interacts_with	gene	0.60
RAS	interacts_with	gene	0.60
GABARAP	interacts_with	gene	0.60
STING1	interacts_with	gene	0.60
PIK3C3	interacts_with	gene	0.60
PI3K	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
AUTOPHAGY	interacts_with	gene	0.60
FIP200	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found