TGFBR1

Understanding Entity Pages

This page aggregates everything SciDEX knows about TGFBR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

TGFBR1 is a gene implicated in neurodegeneration research. Key relationships include: interacts with, associated with, expressed in. Associated with Aging, Als, Cancer. Connected to 61 entities in the SciDEX knowledge graph.

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graph TD
    TGFBR1["<b>TGFBR1</b>"]
    Carcinoma{"Carcinoma"}
    TGFBR1 -->|"associated with"| Carcinoma
    Ms{"Ms"}
    TGFBR1 -->|"associated with"| Ms
    Cancer{"Cancer"}
    TGFBR1 -->|"associated with"| Cancer
    Tumor{"Tumor"}
    TGFBR1 -->|"associated with"| Tumor
    Als{"Als"}
    TGFBR1 -->|"associated with"| Als
    Aging{"Aging"}
    TGFBR1 -->|"interacts with"| Aging
    TGFBR1 -->|"interacts with"| Als
    TGFBR1 -->|"interacts with"| Cancer
    Lymphoma{"Lymphoma"}
    TGFBR1 -->|"interacts with"| Lymphoma
    TGFBR1 -->|"interacts with"| Tumor
    CANCER["CANCER"]
    TGFBR1 -->|"associated with"| CANCER
    BMP2["BMP2"]
    TGFBR1 -->|"associated with"| BMP2
    TGFBR2["TGFBR2"]
    TGFBR2 -->|"associated with"| TGFBR1
    BMP4["BMP4"]
    BMP4 -->|"activates"| TGFBR1
    MIRNAS["MIRNAS"]
    MIRNAS -->|"associated with"| TGFBR1
    MYC["MYC"]
    MYC -->|"associated with"| TGFBR1
    E2F5["E2F5"]
    E2F5 -->|"associated with"| TGFBR1
    CDKN2B["CDKN2B"]
    CDKN2B -->|"associated with"| TGFBR1
    PIK3CA["PIK3CA"]
    PIK3CA -->|"associated with"| TGFBR1
    CDK6["CDK6"]
    CDK6 -->|"associated with"| TGFBR1
    RAB7A["RAB7A"]
    RAB7A -->|"expressed in"| TGFBR1
    AKT["AKT"]
    AKT -->|"associated with"| TGFBR1
    PIK3CA -->|"interacts with"| TGFBR1
    RANKINGS["RANKINGS"]
    RANKINGS -->|"interacts with"| TGFBR1
    style TGFBR1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0