concept

INTERLEUKIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INTERLEUKIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

663Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

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💡 Concept Info

Name	INTERLEUKIN

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Interleukin-6 (IL-6)

entity · 957 words

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Pathway Diagram

graph TD
    INTERLEUKIN["INTERLEUKIN"]
    style INTERLEUKIN fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    INTERLEUKIN -->|"regulates"| Fibrosis["Fibrosis"]
    INTERLEUKIN -->|"target for"| Als["Als"]
    INTERLEUKIN -->|"interacts"| Cancer["Cancer"]
    INTERLEUKIN -->|"target for"| Multiple_Sclerosis["Multiple Sclerosis"]
    INTERLEUKIN -->|"target for"| Neuroinflammation["Neuroinflammation"]
    REL([REL]) -->|"regulates"| INTERLEUKIN
    IL_10([IL-10]) -->|"activates"| INTERLEUKIN
    CERS2([CERS2]) -->|"regulates"| INTERLEUKIN
    IGF1R([IGF1R]) -->|"regulates"| INTERLEUKIN
    DAG1([DAG1]) -->|"regulates"| INTERLEUKIN
    RNA([RNA]) -->|"regulates"| INTERLEUKIN
    ROS([ROS]) -->|"regulates"| INTERLEUKIN
    HSPG2([HSPG2]) -->|"regulates"| INTERLEUKIN
    RIPK1([RIPK1]) -->|"interacts"| INTERLEUKIN
    PPARG([PPARG]) -->|"interacts"| INTERLEUKIN

Outgoing (189)

Target	Relation	Type	Str
Aging	expressed_in	disease	0.60
Cancer	interacts_with	disease	0.60
Als	activates	disease	0.60
Als	biomarker_for	disease	0.60
Atherosclerosis	biomarker_for	disease	0.60
Neuroinflammation	biomarker_for	disease	0.60
Alzheimer	expressed_in	disease	0.60
Atherosclerosis	expressed_in	disease	0.60
Pyroptosis	biomarker_for	disease	0.60
Necroptosis	biomarker_for	disease	0.60
Ferroptosis	biomarker_for	disease	0.60
Fibrosis	interacts_with	disease	0.60
Senescence	expressed_in	disease	0.60
Spinal Cord Injury	activates	disease	0.60
Depression	therapeutic_target	disease	0.60
Epilepsy	therapeutic_target	disease	0.60
Huntington	activates	disease	0.60
Pyroptosis	causes	disease	0.60
Diabetes	activates	disease	0.60
Cancer	expressed_in	disease	0.60
Als	regulates	disease	0.60
Stroke	activates	disease	0.60
Parkinson	expressed_in	disease	0.60
Neuroinflammation	expressed_in	disease	0.60
Cancer	regulates	disease	0.60
Obesity	therapeutic_target	disease	0.60
Stroke	therapeutic_target	disease	0.60
Leukemia	therapeutic_target	disease	0.60
Cancer	associated_with	disease	0.60
Stroke	biomarker_for	disease	0.60
Multiple Sclerosis	therapeutic_target	disease	0.60
Neuroinflammation	therapeutic_target	disease	0.60
Aging	inhibits	disease	0.60
Neurodegeneration	inhibits	disease	0.60
Parkinson	regulates	disease	0.60
Als	inhibits	disease	0.60
Multiple Sclerosis	associated_with	disease	0.60
Parkinson	associated_with	disease	0.60
Anxiety	associated_with	disease	0.60
Neuroinflammation	associated_with	disease	0.60
Aging	biomarker_for	disease	0.60
Fibrosis	biomarker_for	disease	0.60
Senescence	biomarker_for	disease	0.60
Senescence	associated_with	disease	0.60
Aging	protects_against	disease	0.60
Senescence	protects_against	disease	0.60
Neurodegeneration	regulates	disease	0.60
Obesity	activates	disease	0.60
Epilepsy	activates	disease	0.60
Encephalitis	associated_with	disease	0.60

Incoming (474)

Source	Relation	Type	Str
RIPK1	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
WNT	interacts_with	gene	0.60
TFEB	interacts_with	gene	0.60
CFTR	interacts_with	gene	0.60
RICTOR	interacts_with	gene	0.60
ROS	interacts_with	gene	0.60
GRB2	interacts_with	gene	0.60
HSP70	interacts_with	gene	0.60
STAT3	interacts_with	gene	0.60
RB1	interacts_with	gene	0.60
IFN	interacts_with	gene	0.60
AMPK	interacts_with	gene	0.60
DDIT3	interacts_with	gene	0.60
MLST8	interacts_with	gene	0.60
NEURON	activates	gene	0.60
GPR37	activates	gene	0.60
PARKINSON	activates	gene	0.60
PSAP	activates	gene	0.60
DNAJB9	associated_with	gene	0.60
AGING	associated_with	gene	0.60
HSPA1A	associated_with	gene	0.60
RNA	therapeutic_target	gene	0.60
CYTOKINES	therapeutic_target	gene	0.60
IL-6	therapeutic_target	gene	0.60
STING	activates	gene	0.60
CGAS-STING	inhibits	gene	0.60
CGAS	activates	gene	0.60
P16	activates	gene	0.60
P21	activates	gene	0.60
STAT6	protects_against	gene	0.60
DNA	activates	gene	0.60
IL-4	protects_against	gene	0.60
AGING	protects_against	gene	0.60
DEPRESSION	associated_with	gene	0.60
BDNF	associated_with	gene	0.60
GPR109A	expressed_in	gene	0.60
IL-1	expressed_in	gene	0.60
IL-6	expressed_in	gene	0.60
ASC	activates	gene	0.60
CATHEPSINS	activates	gene	0.60
TAU	expressed_in	gene	0.60
SYN1	biomarker_for	gene	0.60
APOPTOSIS	expressed_in	gene	0.60
ROS	biomarker_for	gene	0.60
AUTOPHAGY	activates	gene	0.60
IL-1	interacts_with	gene	0.60
ALZHEIMER	associated_with	gene	0.60
MICROGLIA	associated_with	gene	0.60
MAPK	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning INTERLEUKIN in their description or question text

No additional research found