Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about migraine: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Associated Genes | EPHA5, RPL17 |
| KG Connections | 9 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
Knowledge base pages for this entity
graph TD
MIGRAINE["MIGRAINE"]
Oxidative_stress["Oxidative stress"] -->|"causes"| MIGRAINE
Cerebral_energy_deficiency["Cerebral energy deficiency"] -->|"causes"| MIGRAINE
CCL3["CCL3"] -->|"activates"| MIGRAINE
C1Q["C1Q"] -->|"activates"| MIGRAINE
CHR2["CHR2"] -->|"activates"| MIGRAINE
TNF["TNF"] -->|"regulates"| MIGRAINE
GENES["GENES"] -->|"activates"| MIGRAINE
MICROGLIA["MICROGLIA"] -->|"regulates"| MIGRAINE
ASTROCYTES["ASTROCYTES"] -->|"regulates"| MIGRAINE
IL_6["IL-6"] -->|"regulates"| MIGRAINE| Target | Relation | Type | Str |
|---|---|---|---|
| nitric oxide | disrupts | neurotransmitter | 0.60 |
| ferroptosis | involves | pathway | 0.60 |
| unfolded protein response | involves | pathway | 0.60 |
| neurons | affects | cell_type | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||