pathway

Ampk Signaling

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Ampk Signaling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

376Connections

0Hypotheses

0Analyses

5Outgoing

50Incoming

No summary available yet. View on Wiki →

🔀 Pathway Info

Name	Ampk Signaling
Key Genes/Proteins	AMPK, GENES, AUTOPHAGY, SIRT1, INFLAMMATION, CANCER
Related Diseases	Als, Inflammation, Fibrosis, Cancer

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    AMPK["AMPK"] -->|"activates"| Ampk_Signaling["Ampk Signaling"]
    GENES["GENES"] -->|"activates"| Ampk_Signaling["Ampk Signaling"]
    Als["Als"] -->|"activates"| Ampk_Signaling["Ampk Signaling"]
    AUTOPHAGY["AUTOPHAGY"] -->|"activates"| Ampk_Signaling["Ampk Signaling"]
    style Ampk_Signaling fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (55)

Target	Relation	Type	Str
CEREBELLUM	activates	concept	0.50
Neuron	therapeutic_target	cell_type	0.50
Astrocyte	activates	cell_type	0.50
Neuron	activates	cell_type	0.50
Neuron	regulates	cell_type	0.50

Incoming (321)

Source	Relation	Type	Str
AMPK	activates	gene	1.00
GENES	activates	gene	1.00
Als	activates	disease	1.00
AUTOPHAGY	activates	gene	0.90
Inflammation	activates	disease	0.90
Als	regulates	disease	0.90
Fibrosis	activates	disease	0.80
AMPK	regulates	gene	0.80
SIRT1	activates	gene	0.80
INFLAMMATION	activates	gene	0.80
AMPK	therapeutic_target	gene	0.80
CANCER	therapeutic_target	gene	0.80
Cancer	therapeutic_target	disease	0.80
APOPTOSIS	activates	gene	0.70
NEUROTOXICITY	activates	gene	0.70
OXIDATIVE STRESS	activates	gene	0.70
MTOR	activates	gene	0.70
NF-ΚB	activates	gene	0.70
AUTOPHAGY	regulates	gene	0.70
TNF	activates	gene	0.70
IL-6	activates	gene	0.70
TNF-Α	activates	gene	0.70
MICROGLIA	activates	gene	0.70
Osteoarthritis	activates	disease	0.70
Tumor	activates	disease	0.70
CANCER	activates	gene	0.70
Cancer	activates	disease	0.70
Lung Cancer	activates	disease	0.70
ATG5	activates	gene	0.70
LC3	activates	gene	0.70
P62	activates	gene	0.70
AMPK	contributes_to	gene	0.70
PI3K	activates	gene	0.60
VEGF	activates	gene	0.60
AKT	activates	gene	0.60
EXOSOMES	activates	gene	0.60
Ischemia	activates	disease	0.60
Myocardial Infarction	activates	disease	0.60
Cardiac	activates	disease	0.60
Arrhythmia	activates	disease	0.60
BCL2 FAMILY	activates	gene	0.60
ROS	activates	gene	0.60
BCL2	activates	gene	0.60
NEURON	activates	gene	0.60
AMPK	inhibits	gene	0.60
CHONDROCYTE APOPTOSIS	inhibits	gene	0.60
APOPTOSIS	inhibits	gene	0.60
Osteoarthritis	causes	disease	0.60
NRF2	activates	gene	0.60
AGING	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Ampk Signaling

Understanding Entity Pages

Wiki Pages (20)

Wnt Non-Canonical Signaling Pathways in Neurodegeneration

Niemann-Pick Disease Type C (NPC)

IGF-1 Signaling Pathway in Neurodegeneration

creatine-supplementation-neurodegeneration

Neuroinflammation-Mitochondria Crosstalk Pathway

Neuroinflammation in Amyotrophic Lateral Sclerosis

FGF Signaling Pathway in Neurodegeneration

GLP-1 Signaling Pathway in Neurodegeneration

AMPK Signaling Pathway

MAP1LC3A Gene

Energy Metabolism in Neurodegeneration

PM20D1 Protein

Metabolic Dysfunction in Alzheimer's Disease

CAV1

RRAGB — Ras-Related GTP Binding B

MFSD1

Irisin (FNDC5) - Exercise-Induced Myokine for Neurodegeneration

PLIN1 — Perilipin 1