CXCL12

Understanding Entity Pages

This page aggregates everything SciDEX knows about CXCL12: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CXCL12 is a gene implicated in neurodegeneration research. Key relationships include: associated with, implicated in, activates. Associated with Als, Cancer, Carcinoma. Connected to 59 entities in the SciDEX knowledge graph.

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graph TD
    CXCL12["<b>CXCL12</b>"]
    Als{"Als"}
    CXCL12 -->|"associated with"| Als
    Ms{"Ms"}
    CXCL12 -->|"associated with"| Ms
    Depression{"Depression"}
    CXCL12 -->|"associated with"| Depression
    Inflammation{"Inflammation"}
    CXCL12 -->|"associated with"| Inflammation
    Diabetes{"Diabetes"}
    CXCL12 -->|"inhibits"| Diabetes
    Tumor{"Tumor"}
    CXCL12 -->|"activates"| Tumor
    Cancer{"Cancer"}
    CXCL12 -->|"expressed in"| Cancer
    EGFR["EGFR"]
    CXCL12 -->|"activates"| EGFR
    Apoptosis(["Apoptosis"])
    CXCL12 -->|"activates"| Apoptosis
    SRC["SRC"]
    CXCL12 -->|"expressed in"| SRC
    CD38["CD38"]
    CXCL12 -->|"expressed in"| CD38
    CANCER["CANCER"]
    CXCL12 -->|"expressed in"| CANCER
    DDX5["DDX5"]
    DDX5 -->|"regulates"| CXCL12
    SGK1["SGK1"]
    SGK1 -->|"associated with"| CXCL12
    FKBP5["FKBP5"]
    FKBP5 -->|"associated with"| CXCL12
    A2M["A2M"]
    A2M -->|"associated with"| CXCL12
    AQP4["AQP4"]
    AQP4 -->|"associated with"| CXCL12
    TNF["TNF"]
    TNF -->|"associated with"| CXCL12
    P2RX7["P2RX7"]
    P2RX7 -->|"associated with"| CXCL12
    ISG15["ISG15"]
    ISG15 -->|"associated with"| CXCL12
    STAT1["STAT1"]
    STAT1 -->|"associated with"| CXCL12
    USP18["USP18"]
    USP18 -->|"associated with"| CXCL12
    DIABETES_MELLITUS["DIABETES MELLITUS"]
    DIABETES_MELLITUS -->|"inhibits"| CXCL12
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"associated with"| CXCL12
    style CXCL12 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0