ENDOSOME

Understanding Entity Pages

This page aggregates everything SciDEX knows about ENDOSOME: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

ENDOSOME is a concept in neurodegeneration research. Key relationships include: regulates, activates, associated with. Associated with ALS, Als, Alzheimer. Connected to 134 entities in the SciDEX knowledge graph.

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graph TD
    ENDOSOME["<b>ENDOSOME</b>"]
    ENDOSOME -->|"regulates"| ALS["ALS"]
    ENDOSOME -->|"activates"| Alzheimer["Alzheimer"]
    ENDOSOME -->|"activates"| Tauopathy["Tauopathy"]
    ENDOSOME -->|"regulates"| MITOCHONDRIA["MITOCHONDRIA"]
    ENDOSOME -->|"regulates"| RAB7A["RAB7A"]
    ENDOSOME -->|"regulates"| PINK1["PINK1"]
    ENDOSOME -->|"regulates"| TBK1["TBK1"]
    ENDOSOME -->|"regulates"| ATG9A["ATG9A"]
    ENDOSOME -->|"regulates"| PARKIN["PARKIN"]
    ENDOSOME -->|"regulates"| PTEN["PTEN"]
    ENDOSOME -->|"regulates"| AUTOPHAGY["AUTOPHAGY"]
    ENDOSOME -->|"regulates"| Mitophagy["Mitophagy"]
    VPS16["VPS16"] -->|"participates in"| ENDOSOME
    NF__B["NF-KappaB"] -->|"regulates"| ENDOSOME
    MITOPHAGY["MITOPHAGY"] -->|"regulates"| ENDOSOME
    LYSOSOME["LYSOSOME"] -->|"regulates"| ENDOSOME
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"activates"| ENDOSOME
    CHMP6["CHMP6"] -->|"regulates"| ENDOSOME
    ATG9A -->|"regulates"| ENDOSOME
    TBK1 -->|"regulates"| ENDOSOME
    PARKIN -->|"regulates"| ENDOSOME
    AND["AND"] -->|"regulates"| ENDOSOME
    AUTOPHAGY -->|"regulates"| ENDOSOME
    RAB7A -->|"regulates"| ENDOSOME