autophagy pathway

Understanding Entity Pages

This page aggregates everything SciDEX knows about autophagy pathway: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    autophagy_pathway["autophagy pathway"] -->|"active in"| neurons["neurons"]
    style neurons fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"protects against"| Neuronal_Health["Neuronal Health"]
    style Neuronal_Health fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"mediates"| ferroptosis["ferroptosis"]
    style ferroptosis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"mediates"| phagocytosis["phagocytosis"]
    style phagocytosis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"active in"| endothelial_cells["endothelial cells"]
    style endothelial_cells fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"mediates"| protein_misfolding["protein misfolding"]
    style protein_misfolding fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    autophagy_pathway["autophagy pathway"] -->|"mediates"| ER_stress["ER stress"]
    style ER_stress fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    OPTN["OPTN"] -->|"regulates"| autophagy_pathway["autophagy pathway"]
    style OPTN fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    MTOR["MTOR"] -->|"participates in"| autophagy_pathway["autophagy pathway"]
    style MTOR fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    MTORC1["MTORC1"] -->|"participates in"| autophagy_pathway["autophagy pathway"]
    style MTORC1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    SQSTM1["SQSTM1"] -->|"participates in"| autophagy_pathway["autophagy pathway"]
    style SQSTM1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PI3K["PI3K"] -->|"participates in"| autophagy_pathway["autophagy pathway"]
    style PI3K fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style autophagy_pathway fill:#1b5e20,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold