RTN3

Understanding Entity Pages

This page aggregates everything SciDEX knows about RTN3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

RTN3 (Reticulon 3): ER morphogenesis protein involved in autophagy, APP processing, and neurodegenerative diseases including Alzheimer's and Huntington's disease

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graph TD
    RTN3["RTN3"] -->|"Interacts With"| Dementia["Dementia"]
    RTN3["RTN3"] -->|"Interacts With"| Cardiovascular["Cardiovascular"]
    RTN3["RTN3"] -->|"Interacts With"| Als["Als"]
    RTN3["RTN3"] -->|"Interacts With"| Alzheimer["Alzheimer"]
    RTN3["RTN3"] -->|"Interacts With"| Parkinson["Parkinson"]
    RTN3["RTN3"] -->|"Interacts With"| Ms["Ms"]
    RTN3["RTN3"] -->|"Interacts With"| Amyotrophic_Lateral_Sclerosis["Amyotrophic Lateral Sclerosis"]
    RTN3["RTN3"] -->|"Interacts With"| Frontotemporal_Dementia["Frontotemporal Dementia"]
    CAT["CAT"] -->|"Interacts With"| RTN3["RTN3"]
    OPTN["OPTN"] -->|"Interacts With"| RTN3["RTN3"]
    DNM1L["DNM1L"] -->|"Interacts With"| RTN3["RTN3"]
    CANX["CANX"] -->|"Interacts With"| RTN3["RTN3"]
    LGALS3["LGALS3"] -->|"Interacts With"| RTN3["RTN3"]
    style RTN3 fill:#8d4900,color:#e0e0e0
    style Dementia fill:#b71c1c,color:#e0e0e0
    style Cardiovascular fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Alzheimer fill:#b71c1c,color:#e0e0e0
    style Parkinson fill:#b71c1c,color:#e0e0e0
    style Ms fill:#b71c1c,color:#e0e0e0
    style Amyotrophic_Lateral_Sclerosis fill:#b71c1c,color:#e0e0e0
    style Frontotemporal_Dementia fill:#b71c1c,color:#e0e0e0
    style CAT fill:#8d4900,color:#e0e0e0
    style OPTN fill:#8d4900,color:#e0e0e0
    style DNM1L fill:#8d4900,color:#e0e0e0
    style CANX fill:#8d4900,color:#e0e0e0
    style LGALS3 fill:#8d4900,color:#e0e0e0