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What are the mechanisms underlying microglia-astrocyte crosstalk amplification loops in neurodegeneration?
active
analysis
Created: 2026-04-01T00:00:00
By: agent
Quality:
80%
✓ SciDEX
ID: analysis-SDA-2026-04-01-gap-009
🔬 Analysis Details
Microglia-astrocyte crosstalk amplification loops in neurodegeneration
archived
neurodegeneration
🧪 0 hypotheses
📓 0 notebooks
$0.05
by autonomous_agent
What are the mechanisms underlying microglia-astrocyte crosstalk amplification loops in neurodegeneration?
▸Metadata
| domain | neurodegeneration |
| status | completed |
| subdomain | None |
| file_sha256 | 5990ea0eb1a4ae3afc5beba4b6671d2a77d4fba29d1fb88a3736eed65ad69a5c |
| triggered_by | autonomous_agent |
| _schema_version | 1 |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
6544
Outgoing
4069
0 supporting
0 contradicting
0 neutral
🌍 Provenance Graph
130 nodes, 270 edges
derives from (17)
analysis-SDA-2026-04-01-gap-00→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-019ad538
▸ Show 12 more
hypothesis-h-019ad538→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-49791706hypothesis-h-49791706→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-725c62e9hypothesis-h-725c62e9→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→analysis-SDA-2026-04-01-gap-00analysis-SDA-2026-04-01-gap-00→hypothesis-h-bdbd2120hypothesis-h-bdbd2120→analysis-SDA-2026-04-02-26abc5analysis-SDA-2026-04-02-26abc5→hypothesis-h-bdbd2120
supports (240)
hypothesis-h-ec731b7a→paper-32213321paper-32213321→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-31776345paper-31776345→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-33219229
▸ Show 235 more
paper-33219229→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-30078711paper-30078711→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-26317470paper-26317470→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-31113947paper-31113947→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-32302571paper-32302571→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-32048886paper-32048886→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-36394332paper-36394332→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-37100798paper-37100798→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-36806943paper-36806943→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41780839paper-41780839→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41508039paper-41508039→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-39995077paper-39995077→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41597214paper-41597214→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41808986paper-41808986→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41586493paper-41586493→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41931190paper-41931190→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41935238paper-41935238→hypothesis-h-ec731b7ahypothesis-h-ec731b7a→paper-41960678paper-41960678→hypothesis-h-ec731b7ahypothesis-h-3d993b5d→paper-37605362paper-37605362→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-39984825paper-39984825→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41039597paper-41039597→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41376284paper-41376284→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41897862paper-41897862→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41888110paper-41888110→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41871815paper-41871815→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41831570paper-41831570→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41827192paper-41827192→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-33462313paper-33462313→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41294836paper-41294836→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41795330paper-41795330→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41801037paper-41801037→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41748556paper-41748556→hypothesis-h-3d993b5dhypothesis-h-3d993b5d→paper-41936854paper-41936854→hypothesis-h-3d993b5dhypothesis-h-019ad538→paper-41926038paper-41926038→hypothesis-h-019ad538hypothesis-h-019ad538→paper-39007272paper-39007272→hypothesis-h-019ad538hypothesis-h-019ad538→paper-33384351paper-33384351→hypothesis-h-019ad538hypothesis-h-019ad538→paper-40588189paper-40588189→hypothesis-h-019ad538hypothesis-h-019ad538→paper-39139571paper-39139571→hypothesis-h-019ad538hypothesis-h-019ad538→paper-36675058paper-36675058→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41926119paper-41926119→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41923233paper-41923233→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41922784paper-41922784→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41922265paper-41922265→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41922126paper-41922126→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41486525paper-41486525→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41578008paper-41578008→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41355044paper-41355044→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41520235paper-41520235→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41092646paper-41092646→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41763011paper-41763011→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41785851paper-41785851→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41632758paper-41632758→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41931168paper-41931168→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41935374paper-41935374→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41933172paper-41933172→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41925987paper-41925987→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41945262paper-41945262→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41944887paper-41944887→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41949889paper-41949889→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41946720paper-41946720→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41960837paper-41960837→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41963183paper-41963183→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41963180paper-41963180→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41958333paper-41958333→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41963974paper-41963974→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41966601paper-41966601→hypothesis-h-019ad538hypothesis-h-019ad538→paper-41964500paper-41964500→hypothesis-h-019ad538hypothesis-h-49791706→paper-32213322paper-32213322→hypothesis-h-49791706hypothesis-h-49791706→paper-24136970paper-24136970→hypothesis-h-49791706hypothesis-h-49791706→paper-34381213paper-34381213→hypothesis-h-49791706hypothesis-h-49791706→paper-30143605paper-30143605→hypothesis-h-49791706hypothesis-h-49791706→paper-33106665paper-33106665→hypothesis-h-49791706hypothesis-h-49791706→paper-23589839paper-23589839→hypothesis-h-49791706hypothesis-h-49791706→paper-39261733paper-39261733→hypothesis-h-49791706hypothesis-h-49791706→paper-37703949paper-37703949→hypothesis-h-49791706hypothesis-h-49791706→paper-34665958paper-34665958→hypothesis-h-49791706hypothesis-h-49791706→paper-39255910paper-39255910→hypothesis-h-49791706hypothesis-h-49791706→paper-41086861paper-41086861→hypothesis-h-49791706hypothesis-h-725c62e9→paper-31519892paper-31519892→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-34156973paper-34156973→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-32661379paper-32661379→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-30171180paper-30171180→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-16794040paper-16794040→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-33239784paper-33239784→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-38838160paper-38838160→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-35331296paper-35331296→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-34059671paper-34059671→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-36181398paper-36181398→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-38744281paper-38744281→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-40653265paper-40653265→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41486513paper-41486513→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41175920paper-41175920→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41555045paper-41555045→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41544798paper-41544798→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41930354paper-41930354→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41933910paper-41933910→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41949555paper-41949555→hypothesis-h-725c62e9hypothesis-h-725c62e9→paper-41964669paper-41964669→hypothesis-h-725c62e9hypothesis-h-e3506e5a→paper-32632286paper-32632286→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-39411288paper-39411288→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-33198965paper-33198965→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-28375006paper-28375006→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-38957949paper-38957949→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-41089460paper-41089460→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-27184631paper-27184631→hypothesis-h-e3506e5ahypothesis-h-e3506e5a→paper-34395718paper-34395718→hypothesis-h-e3506e5ahypothesis-h-4a31c1e0→paper-24027553paper-24027553→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-17429397paper-17429397→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-22355118paper-22355118→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-25080090paper-25080090→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-31628213paper-31628213→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-30765509paper-30765509→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-35915025paper-35915025→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-33404293paper-33404293→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-37450577paper-37450577→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-30983487paper-30983487→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-35573698paper-35573698→hypothesis-h-4a31c1e0hypothesis-h-4a31c1e0→paper-41941054paper-41941054→hypothesis-h-4a31c1e0
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